Detectability of Fiducials' Positions for Real-time Target Tracking System Equipping with a Standard Linac for Multiple Fiducial Markers

Overview

Journal J Appl Clin Med Phys

Specialties Biophysics
General Medicine

Date 2020 Oct 15

PMID 33058408

Citations 1

Authors

Shunsuke Ono

Yoshihiro Ueda

Shingo Ohira

Masaru Isono

Iori Sumida

Shoki Inui

Masahiro Morimoto

Reiko Ashida

Masayoshi Miyazaki

Kazuhiko Ogawa

Teruki Teshima

Affiliations

Soon will be listed here.

Abstract

Purpose: To investigate the detectability of fiducial markers' positions for real-time target tracking system equipping with a standard linac. The hypothesis is that the detectability depends on the type of fiducial marker and the gantry angle of acquired triggered images.

Methods: Three types of ball fiducials and four slim fiducials with lengths of 3 and 5 mm were prepared for this study. Triggered images with three similar fiducials were acquired at every 10° during the conformal arc irradiation to detect the target position. Although only one type of arrangement was prepared for the ball fiducials, a three-type arrangement was prepared for the slim fiducials, such as parallel, orthogonal, and oblique with 45° to the gantry-couch direction. To measure the detectability of the real-time target tracking system for each fiducial and arrangement, detected marker positions were compared with expected marker positions at every angle of acquired triggered images.

Results: For the ball-type fiducial, the maximum difference between the detected marker positions and expected marker positions was 0.3 mm in all directions. For the slim fiducial arranged parallel and oblique with 45°, the maximum difference was 0.4 mm in all directions. When each slim fiducial was arranged orthogonal to the gantry-couch direction, the maximum difference was 1.5 mm for the length of 3 mm, and 3.2 mm for the length of 5 mm.

Conclusions: The detectability of fiducial markers' positions for the real-time target tracking system equipping with a standard linac depends on the form and insertion angles of the fiducials.

Citing Articles

Investigation of fiducial marker recognition possibility by water equivalent length in real-time tracking radiotherapy.

Yasue K, Fuse H, Asano Y, Kato M, Shinoda K, Ikoma H Jpn J Radiol. 2021; 40(3):318-325.

PMID: 34655387 DOI: 10.1007/s11604-021-01207-4.

References

Dehnad H, Nederveen A, van der Heide U, Jeroen A van Moorselaar R, Hofman P, Lagendijk J . Clinical feasibility study for the use of implanted gold seeds in the prostate as reliable positioning markers during megavoltage irradiation. Radiother Oncol. 2003; 67(3):295-302. DOI: 10.1016/s0167-8140(03)00078-1. View

Letourneau D, Martinez A, Lockman D, Yan D, Vargas C, Ivaldi G . Assessment of residual error for online cone-beam CT-guided treatment of prostate cancer patients. Int J Radiat Oncol Biol Phys. 2005; 62(4):1239-46. DOI: 10.1016/j.ijrobp.2005.03.035. View

Shchory T, Schifter D, Lichtman R, Neustadter D, Corn B . Tracking accuracy of a real-time fiducial tracking system for patient positioning and monitoring in radiation therapy. Int J Radiat Oncol Biol Phys. 2010; 78(4):1227-34. DOI: 10.1016/j.ijrobp.2010.01.067. View

Inoue M, Shiomi H, Iwata H, Taguchi J, Okawa K, Kikuchi C . Development of system using beam's eye view images to measure respiratory motion tracking errors in image-guided robotic radiosurgery system. J Appl Clin Med Phys. 2015; 16(1):5049. PMC: 5689998. DOI: 10.1120/jacmp.v16i1.5049. View

Seppenwoolde Y, Wunderink W, Wunderink-van Veen S, Storchi P, Mendez Romero A, Heijmen B . Treatment precision of image-guided liver SBRT using implanted fiducial markers depends on marker-tumour distance. Phys Med Biol. 2011; 56(17):5445-68. DOI: 10.1088/0031-9155/56/17/001. View

Chuong M, Springett G, Freilich J, Park C, Weber J, Mellon E . Stereotactic body radiation therapy for locally advanced and borderline resectable pancreatic cancer is effective and well tolerated. Int J Radiat Oncol Biol Phys. 2013; 86(3):516-22. DOI: 10.1016/j.ijrobp.2013.02.022. View

Lu X, Shanmugham L, Mahadevan A, Nedea E, Stevenson M, Kaplan I . Organ deformation and dose coverage in robotic respiratory-tracking radiotherapy. Int J Radiat Oncol Biol Phys. 2008; 71(1):281-9. DOI: 10.1016/j.ijrobp.2007.12.042. View

Iizuka Y, Matsuo Y, Ishihara Y, Akimoto M, Tanabe H, Takayama K . Dynamic tumor-tracking radiotherapy with real-time monitoring for liver tumors using a gimbal mounted linac. Radiother Oncol. 2015; 117(3):496-500. DOI: 10.1016/j.radonc.2015.08.033. View

Kindblom J, Ekelund-Olvenmark A, Syren H, Iustin R, Braide K, Frank-Lissbrant I . High precision transponder localization using a novel electromagnetic positioning system in patients with localized prostate cancer. Radiother Oncol. 2008; 90(3):307-11. DOI: 10.1016/j.radonc.2008.08.018. View

10.

Lips I, van der Heide U, Haustermans K, van Lin E, Pos F, Franken S . Single blind randomized phase III trial to investigate the benefit of a focal lesion ablative microboost in prostate cancer (FLAME-trial): study protocol for a randomized controlled trial. Trials. 2011; 12:255. PMC: 3286435. DOI: 10.1186/1745-6215-12-255. View

11.

Kupelian P, Willoughby T, Mahadevan A, Djemil T, Weinstein G, Jani S . Multi-institutional clinical experience with the Calypso System in localization and continuous, real-time monitoring of the prostate gland during external radiotherapy. Int J Radiat Oncol Biol Phys. 2006; 67(4):1088-98. DOI: 10.1016/j.ijrobp.2006.10.026. View

12.

Miyamoto N, Maeda K, Abo D, Morita R, Takao S, Matsuura T . Quantitative evaluation of image recognition performance of fiducial markers in real-time tumor-tracking radiation therapy. Phys Med. 2019; 65:33-39. DOI: 10.1016/j.ejmp.2019.08.004. View

13.

Rosario T, van der Weide L, Admiraal M, Piet M, Slotman B, Cuijpers J . Toward planning target volume margin reduction for the prostate using intrafraction motion correction with online kV imaging and automatic detection of implanted gold seeds. Pract Radiat Oncol. 2018; 8(6):422-428. DOI: 10.1016/j.prro.2018.04.008. View

14.

Brunner T, Nestle U, Grosu A, Partridge M . SBRT in pancreatic cancer: what is the therapeutic window?. Radiother Oncol. 2014; 114(1):109-16. DOI: 10.1016/j.radonc.2014.10.015. View

15.

Bedos L, Riou O, Ailleres N, Braccini A, Molinier J, Llacer Moscardo C . Evaluation of reproducibility of tumor repositioning during multiple breathing cycles for liver stereotactic body radiotherapy treatment. Rep Pract Oncol Radiother. 2017; 22(2):132-140. PMC: 5411957. DOI: 10.1016/j.rpor.2016.07.007. View

16.

Murray L, Lilley J, Thompson C, Cosgrove V, Mason J, Sykes J . Prostate stereotactic ablative radiation therapy using volumetric modulated arc therapy to dominant intraprostatic lesions. Int J Radiat Oncol Biol Phys. 2014; 89(2):406-15. PMC: 4018668. DOI: 10.1016/j.ijrobp.2014.01.042. View

17.

Koong A, Le Q, Ho A, Fong B, Fisher G, Cho C . Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys. 2004; 58(4):1017-21. DOI: 10.1016/j.ijrobp.2003.11.004. View

18.

Vinogradskiy Y, Goodman K, Schefter T, Miften M, Jones B . The Clinical and Dosimetric Impact of Real-Time Target Tracking in Pancreatic SBRT. Int J Radiat Oncol Biol Phys. 2018; 103(1):268-275. PMC: 6596417. DOI: 10.1016/j.ijrobp.2018.08.021. View