Clinical Efficacy of Platelet-rich Plasma As Adjuvant Therapy in Patients Undergoing Arthroscopic Repair of Meniscal Injury

Overview

Journal J Int Med Res

Publisher Sage Publications

Specialty General Medicine

Date 2020 Sep 23

PMID 32962482

Citations 9

Authors

Yaodong Wang

Chi Yao

Zhuo Yang

Wenlai Guo

Affiliations

Soon will be listed here.

Abstract

Objective: The clinical efficacy of platelet-rich plasma (PRP) as adjuvant therapy in patients undergoing arthroscopic repair of meniscal injury remains controversial. This meta-analysis was performed to evaluate the clinical efficacy of PRP in the treatment of meniscal injury and provide evidence for the selection of clinical treatment options.

Methods: A computer-based search of the PubMed, Embase, and Cochrane Library databases was performed to retrieve articles using the search terms "platelet-rich plasma" and "menisci." Quality evaluation and data extraction were performed. The combined effect was assessed using RevMan version 5.3 software.

Results: Three randomized controlled trials and three cohort studies involving 293 patients were included in the meta-analysis. There were no significant differences in the International Knee Documentation Committee score or Lysholm score between the experimental and control groups. The failure rate and visual analog scale score were significantly lower and the degree of active flexion was significantly higher in the experimental group than in the control group.

Conclusion: The findings of this meta-analysis suggest that PRP injection can effectively enhance the efficacy of arthroscopic repair of meniscal injury, reduce the failure rate and severity of pain, and improve active flexion.

Citing Articles

Efficacy of platelet-rich plasma in meniscal repair surgery: a systematic review of randomized controlled trials.

Utrilla G, Degano I, DAmbrosi R J Orthop Traumatol. 2024; 25(1):63.

PMID: 39694969 PMC: 11656006. DOI: 10.1186/s10195-024-00799-7.

Ultrasound-guided injection using leucocyte-rich platelet-rich plasma for treatment of meniscal injuries in a duathlete: a case report.

de Castro J, Wang D, Celis P, Strakowski J Regen Med. 2024; 19(11):523-528.

PMID: 39474833 PMC: 11633417. DOI: 10.1080/17460751.2024.2418705.

The Use of Platelet-Rich Plasma Augmentation in Meniscus Repair Results in a Lower Failure Rate than in the Control Group: A Systematic Review From Meta-analysis.

Sakti M, Paturusi I, Singjie L, Kusuma S Arthrosc Sports Med Rehabil. 2024; 6(4):100934.

PMID: 39421348 PMC: 11480798. DOI: 10.1016/j.asmr.2024.100934.

Biologic Augmentation of Isolated Meniscal Repair.

Chen K, Aggarwal S, Baker H, Athiviraham A Curr Rev Musculoskelet Med. 2024; 17(7):223-234.

PMID: 38652368 PMC: 11156815. DOI: 10.1007/s12178-024-09898-8.

Current Status and Advancements in Platelet-Rich Plasma Therapy.

Pretorius J, Habash M, Ghobrial B, Alnajjar R, Ellanti P Cureus. 2023; 15(10):e47176.

PMID: 38021947 PMC: 10652151. DOI: 10.7759/cureus.47176.

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