Beneficial Effects of Anti-Oxidative Herbal Medicines in Diabetic Patients Infected with COVID-19: A Hypothesis

Overview

Journal Diabetes Metab Syndr Obes

Publisher Dove Medical Press

Specialty Endocrinology

Date 2020 Sep 18

PMID 32943897

Citations 7

Authors

Ozra Tabatabaei-Malazy

Mohammad Abdollahi

Bagher Larijani

Affiliations

Soon will be listed here.

Abstract

During the pandemic of Coronavirus Disease 2019 (COVID-19), it is critical to introduce potential medical treatments. Anti-oxidative herbal medicines with evidence-based beneficial impacts in the treatment of diabetes mellitus can be suggested as an adjuvant therapy to its conventional treatments in patients infected with COVID-19.

Citing Articles

Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus.

Adha S, Afifah N, Latarissa I, Iftinan G, Kusuma A, Febriyanti R Diabetes Metab Syndr Obes. 2025; 18():135-146.

PMID: 39840393 PMC: 11746946. DOI: 10.2147/DMSO.S498774.

Antioxidative and Anti-inflammatory Effects of Plant-derived Hypoglycemic Medicines: An Systematic Review.

Adel-Mehraban M, Tabatabaei-Malazy O, Manayi A, Alatab S, Mohseni S, Fana S Curr Top Med Chem. 2024; 24(16):1408-1450.

PMID: 38644706 DOI: 10.2174/0115680266295032240415064750.

Oxidative stress and COVID-19-associated neuronal dysfunction: mechanisms and therapeutic implications.

Bowen D, Pathak S, Nadar R, Parise R, Ramesh S, Govindarajulu M Acta Biochim Biophys Sin (Shanghai). 2023; 55(8):1153-1167.

PMID: 37357527 PMC: 10465323. DOI: 10.3724/abbs.2023085.

Scientometric assessment of scientific documents published in 2020 on herbal medicines used for COVID-19.

Atlasi R, Ramezani A, Tabatabaei-Malazy O, Alatab S, Oveissi V, Larijani B J Herb Med. 2022; 35:100588.

PMID: 35847990 PMC: 9272664. DOI: 10.1016/j.hermed.2022.100588.

Does Oxidative Stress Management Help Alleviation of COVID-19 Symptoms in Patients Experiencing Diabetes?.

Paul A, Hossain M, Mahboob T, Nissapatorn V, Wilairatana P, Jahan R Nutrients. 2022; 14(2).

PMID: 35057501 PMC: 8780958. DOI: 10.3390/nu14020321.

References

Lin L, Hsu W, Lin C . Antiviral natural products and herbal medicines. J Tradit Complement Med. 2014; 4(1):24-35. PMC: 4032839. DOI: 10.4103/2225-4110.124335. View

Ciavarella C, Motta I, Valente S, Pasquinelli G . Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-γ as Candidates for Cytokine Storm Modulation in COVID-19 Disease. Molecules. 2020; 25(9). PMC: 7248959. DOI: 10.3390/molecules25092076. View

van den Brand J, Haagmans B, van Riel D, Osterhaus A, Kuiken T . The pathology and pathogenesis of experimental severe acute respiratory syndrome and influenza in animal models. J Comp Pathol. 2014; 151(1):83-112. PMC: 7094469. DOI: 10.1016/j.jcpa.2014.01.004. View

Wen C, Kuo Y, Jan J, Liang P, Wang S, Liu H . Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus. J Med Chem. 2007; 50(17):4087-95. DOI: 10.1021/jm070295s. View

Lin C, Lin K, Hsieh T, Shiu S, Li J . Severe acute respiratory syndrome coronavirus 3C-like protease-induced apoptosis. FEMS Immunol Med Microbiol. 2006; 46(3):375-80. PMC: 7110344. DOI: 10.1111/j.1574-695X.2006.00045.x. View

Tootee A, Nasli Esfahani E, Larijani B . Diabetes management during Ramadan amid Covid-19 pandemic. Daru. 2020; 28(2):795-798. PMC: 7316426. DOI: 10.1007/s40199-020-00357-6. View

Ayati N, Saiyarsarai P, Nikfar S . Short and long term impacts of COVID-19 on the pharmaceutical sector. Daru. 2020; 28(2):799-805. PMC: 7332346. DOI: 10.1007/s40199-020-00358-5. View

Azadmehr A, Hajiaghaee R, Zohal M, Maliji G . Protective effects of Scrophularia striata in Ovalbumin-induced mice asthma model. Daru. 2013; 21(1):56. PMC: 3751247. DOI: 10.1186/2008-2231-21-56. View

Bule M, Abdurahman A, Nikfar S, Abdollahi M, Amini M . Antidiabetic effect of quercetin: A systematic review and meta-analysis of animal studies. Food Chem Toxicol. 2019; 125:494-502. DOI: 10.1016/j.fct.2019.01.037. View

10.

Gonzalez-Gallego J, Sanchez-Campos S, Tunon M . Anti-inflammatory properties of dietary flavonoids. Nutr Hosp. 2007; 22(3):287-93. View

11.

Shojaei A, Salari P . COVID-19 and off label use of drugs: an ethical viewpoint. Daru. 2020; 28(2):789-793. PMC: 7207985. DOI: 10.1007/s40199-020-00351-y. View

12.

Nguyen T, Woo H, Kang H, Nguyen V, Kim Y, Kim D . Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris. Biotechnol Lett. 2012; 34(5):831-8. PMC: 7087583. DOI: 10.1007/s10529-011-0845-8. View

13.

Khomich O, Kochetkov S, Bartosch B, Ivanov A . Redox Biology of Respiratory Viral Infections. Viruses. 2018; 10(8). PMC: 6115776. DOI: 10.3390/v10080392. View

14.

Macready A, George T, Chong M, Alimbetov D, Jin Y, Vidal A . Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease--FLAVURS: a randomized controlled trial. Am J Clin Nutr. 2014; 99(3):479-89. DOI: 10.3945/ajcn.113.074237. View

15.

Chen Z, Nakamura T . Statistical evidence for the usefulness of Chinese medicine in the treatment of SARS. Phytother Res. 2004; 18(7):592-4. DOI: 10.1002/ptr.1485. View

16.

Lu R, Zhao X, Li J, Niu P, Yang B, Wu H . Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020; 395(10224):565-574. PMC: 7159086. DOI: 10.1016/S0140-6736(20)30251-8. View

17.

Yang Y, Islam M, Wang J, Li Y, Chen X . Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective. Int J Biol Sci. 2020; 16(10):1708-1717. PMC: 7098036. DOI: 10.7150/ijbs.45538. View

18.

Imai Y, Kuba K, Neely G, Yaghubian-Malhami R, Perkmann T, van Loo G . Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell. 2008; 133(2):235-49. PMC: 7112336. DOI: 10.1016/j.cell.2008.02.043. View

19.

Gupta S, Patchva S, Koh W, Aggarwal B . Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol. 2011; 39(3):283-99. PMC: 3288651. DOI: 10.1111/j.1440-1681.2011.05648.x. View

20.

Panahi Y, Hosseini M, Khalili N, Naimi E, Majeed M, Sahebkar A . Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis. Clin Nutr. 2015; 34(6):1101-8. DOI: 10.1016/j.clnu.2014.12.019. View