The Later Stages of Viral Infection: An Undiscovered Country of Host Dependency Factors

Overview

Journal PLoS Pathog

Specialty Microbiology

Date 2020 Aug 26

PMID 32841303

Citations 5

Authors

Cason R King

Andrew Mehle

Affiliations

Soon will be listed here.

Citing Articles

A virally encoded high-resolution screen of cytomegalovirus dependencies.

Finkel Y, Nachshon A, Aharon E, Arazi T, Simonovsky E, Dobesova M Nature. 2024; 630(8017):712-719.

PMID: 38839957 DOI: 10.1038/s41586-024-07503-z.

Systematic review and meta-analysis of genome-wide pooled CRISPR screens to identify host factors involved in influenza A virus infection.

Maes A, Botzki A, Mathys J, Impens F, Saelens X J Virol. 2024; 98(5):e0185723.

PMID: 38567969 PMC: 11257101. DOI: 10.1128/jvi.01857-23.

Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection.

King C, Liu Y, Amato K, Schaack G, Mickelson C, Sanders A Cell Host Microbe. 2023; 31(9):1552-1567.e8.

PMID: 37652009 PMC: 10528757. DOI: 10.1016/j.chom.2023.08.001.

Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection.

King C, Liu Y, Amato K, Schaack G, Hu T, Smith J bioRxiv. 2023; .

PMID: 36798235 PMC: 9934597. DOI: 10.1101/2023.02.07.527556.

In silico prediction of HIV-1-host molecular interactions and their directionality.

Chai H, Gu Q, Hughes J, Robertson D PLoS Comput Biol. 2022; 18(2):e1009720.

PMID: 35134057 PMC: 8856524. DOI: 10.1371/journal.pcbi.1009720.

References

Ooi Y, Majzoub K, Flynn R, Mata M, Diep J, Li J . An RNA-centric dissection of host complexes controlling flavivirus infection. Nat Microbiol. 2019; 4(12):2369-2382. PMC: 6879806. DOI: 10.1038/s41564-019-0518-2. View

Chavez A, Tuttle M, Pruitt B, Ewen-Campen B, Chari R, Ter-Ovanesyan D . Comparison of Cas9 activators in multiple species. Nat Methods. 2016; 13(7):563-567. PMC: 4927356. DOI: 10.1038/nmeth.3871. View

Huang H, Santoso N, Power D, Simpson S, Dieringer M, Miao H . FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency. J Biol Chem. 2015; 290(45):27297-27310. PMC: 4646377. DOI: 10.1074/jbc.M115.652339. View

Doench J . Am I ready for CRISPR? A user's guide to genetic screens. Nat Rev Genet. 2017; 19(2):67-80. DOI: 10.1038/nrg.2017.97. View

Baillie J . Translational genomics. Targeting the host immune response to fight infection. Science. 2014; 344(6186):807-8. DOI: 10.1126/science.1255074. View

Guo R, Jiang C, Zhang Y, Govande A, Trudeau S, Chen F . MYC Controls the Epstein-Barr Virus Lytic Switch. Mol Cell. 2020; 78(4):653-669.e8. PMC: 7245572. DOI: 10.1016/j.molcel.2020.03.025. View

Carette J, Guimaraes C, Varadarajan M, Park A, Wuethrich I, Godarova A . Haploid genetic screens in human cells identify host factors used by pathogens. Science. 2009; 326(5957):1231-5. DOI: 10.1126/science.1178955. View

Ma Y, Walsh M, Bernhardt K, Ashbaugh C, Trudeau S, Ashbaugh I . CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors. Cell Host Microbe. 2017; 21(5):580-591.e7. PMC: 8938989. DOI: 10.1016/j.chom.2017.04.005. View

Tripathi S, Pohl M, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein D . Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. Cell Host Microbe. 2015; 18(6):723-35. PMC: 4829074. DOI: 10.1016/j.chom.2015.11.002. View

10.

Brelot A, Chakrabarti L . CCR5 Revisited: How Mechanisms of HIV Entry Govern AIDS Pathogenesis. J Mol Biol. 2018; 430(17):2557-2589. DOI: 10.1016/j.jmb.2018.06.027. View

11.

Yeo N, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D . An enhanced CRISPR repressor for targeted mammalian gene regulation. Nat Methods. 2018; 15(8):611-616. PMC: 6129399. DOI: 10.1038/s41592-018-0048-5. View

12.

Harvey R, Brown K, Zhang Q, Gartland M, Walton L, Talarico C . GSK983: a novel compound with broad-spectrum antiviral activity. Antiviral Res. 2009; 82(1):1-11. PMC: 7114156. DOI: 10.1016/j.antiviral.2008.12.015. View

13.

Wright A, Nunez J, Doudna J . Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering. Cell. 2016; 164(1-2):29-44. DOI: 10.1016/j.cell.2015.12.035. View

14.

Nunez J, Harrington L, Doudna J . Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering. ACS Chem Biol. 2016; 11(3):681-8. DOI: 10.1021/acschembio.5b01019. View

15.

Zhang R, Kim A, Fox J, Nair S, Basore K, Klimstra W . Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature. 2018; 557(7706):570-574. PMC: 5970976. DOI: 10.1038/s41586-018-0121-3. View

16.

Carette J, Raaben M, Wong A, Herbert A, Obernosterer G, Mulherkar N . Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature. 2011; 477(7364):340-3. PMC: 3175325. DOI: 10.1038/nature10348. View

17.

Pillay S, Meyer N, Puschnik A, Davulcu O, Diep J, Ishikawa Y . An essential receptor for adeno-associated virus infection. Nature. 2016; 530(7588):108-12. PMC: 4962915. DOI: 10.1038/nature16465. View

18.

Jackson A, Linsley P . Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat Rev Drug Discov. 2010; 9(1):57-67. DOI: 10.1038/nrd3010. View

19.

Duggal N, Emerman M . Evolutionary conflicts between viruses and restriction factors shape immunity. Nat Rev Immunol. 2012; 12(10):687-95. PMC: 3690816. DOI: 10.1038/nri3295. View

20.

Konermann S, Brigham M, Trevino A, Joung J, Abudayyeh O, Barcena C . Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 2014; 517(7536):583-8. PMC: 4420636. DOI: 10.1038/nature14136. View