AI4COVID-19: AI Enabled Preliminary Diagnosis for COVID-19 from Cough Samples Via an App
Overview
Authors
Affiliations
Background: The inability to test at scale has become humanity's Achille's heel in the ongoing war against the COVID-19 pandemic. A scalable screening tool would be a game changer. Building on the prior work on cough-based diagnosis of respiratory diseases, we propose, develop and test an Artificial Intelligence (AI)-powered screening solution for COVID-19 infection that is deployable via a smartphone app. The app, named AI4COVID-19 records and sends three 3-s cough sounds to an AI engine running in the cloud, and returns a result within 2 min.
Methods: Cough is a symptom of over thirty non-COVID-19 related medical conditions. This makes the diagnosis of a COVID-19 infection by cough alone an extremely challenging multidisciplinary problem. We address this problem by investigating the distinctness of pathomorphological alterations in the respiratory system induced by COVID-19 infection when compared to other respiratory infections. To overcome the COVID-19 cough training data shortage we exploit transfer learning. To reduce the misdiagnosis risk stemming from the complex dimensionality of the problem, we leverage a multi-pronged mediator centered risk-averse AI architecture.
Results: Results show AI4COVID-19 can distinguish among COVID-19 coughs and several types of non-COVID-19 coughs. The accuracy is promising enough to encourage a large-scale collection of labeled cough data to gauge the generalization capability of AI4COVID-19. AI4COVID-19 is not a clinical grade testing tool. Instead, it offers a screening tool deployable anytime, anywhere, by anyone. It can also be a clinical decision assistance tool used to channel clinical-testing and treatment to those who need it the most, thereby saving more lives.
Ayappan G, Anila S Sci Rep. 2025; 15(1):2271.
PMID: 39824893 PMC: 11742063. DOI: 10.1038/s41598-025-85140-w.
Gawande M, Zade N, Kumar P, Gundewar S, Weerarathna I, Verma P Mol Biomed. 2025; 6(1):1.
PMID: 39747786 PMC: 11695538. DOI: 10.1186/s43556-024-00238-3.
Husssain S, Ayoub M, Wahid J, Khan A, Alabrah A, Amran G Sci Rep. 2024; 14(1):25207.
PMID: 39448760 PMC: 11502923. DOI: 10.1038/s41598-024-76639-9.
Low-cost and convenient screening of disease using analysis of physical measurements and recordings.
Chandra J, Lin R, Kancherla D, Scott S, Sul D, Andrade D PLOS Digit Health. 2024; 3(9):e0000574.
PMID: 39298384 PMC: 11412657. DOI: 10.1371/journal.pdig.0000574.
Current Diagnostic Techniques for Pneumonia: A Scoping Review.
Kanwal K, Asif M, Khalid S, Liu H, Qurashi A, Abdullah S Sensors (Basel). 2024; 24(13).
PMID: 39001069 PMC: 11244398. DOI: 10.3390/s24134291.