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The Novel Coronavirus 2019-nCoV: Its Evolution and Transmission into Humans Causing Global COVID-19 Pandemic

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Date 2020 Aug 25
PMID 32837521
Citations 14
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Abstract

A novel coronavirus strain 2019-nCoV has caused a rapid global pandemic-COVID-19. Scientists have taken onto the task of characterizing this new virus and understanding how this virus has transmitted to humans. All preliminary studies have found some striking similarities between this new virus and the SARS-CoV that caused a similar kind of epidemic in 2002-2003. Through bioinformatics tools, a great deal of information has been gathered about the origin, evolution and zoonosis of this virus. We, in this review, report the symptoms, mode of transmission and available and putative treatments to tackle 2019-nCoV infections. We also comprehensively summarize all the information so far made available regarding the genome, evolution and zoonosis of this virus.

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References
1.
Lu R, Zhao X, Li J, Niu P, Yang B, Wu H . Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020; 395(10224):565-574. PMC: 7159086. DOI: 10.1016/S0140-6736(20)30251-8. View

2.
Zeng Z, Deng F, Shi K, Ye G, Wang G, Fang L . Dimerization of Coronavirus nsp9 with Diverse Modes Enhances Its Nucleic Acid Binding Affinity. J Virol. 2018; 92(17). PMC: 6096807. DOI: 10.1128/JVI.00692-18. View

3.
Cyranoski D . Did pangolins spread the China coronavirus to people?. Nature. 2021; . DOI: 10.1038/d41586-020-00364-2. View

4.
Liu P, Chen W, Chen J . Viral Metagenomics Revealed Sendai Virus and Coronavirus Infection of Malayan Pangolins (). Viruses. 2019; 11(11). PMC: 6893680. DOI: 10.3390/v11110979. View

5.
Xie J, Li Y, Shen X, Goh G, Zhu Y, Cui J . Dampened STING-Dependent Interferon Activation in Bats. Cell Host Microbe. 2018; 23(3):297-301.e4. PMC: 7104992. DOI: 10.1016/j.chom.2018.01.006. View