Investigation of Genus As a New Source of Antimycobaterial Agents

Overview

Journal Future Sci OA

Specialty Biotechnology

Date 2020 Aug 18

PMID 32802394

Citations 5

Authors

Jessica Aparecida Alves

Fariza Abrao

Thais da Silva Moraes

Jaqueline Lopes Damasceno

Marcos Fernando Dos Santos Moraes

Rodrigo Cassio Sola Veneziani

Sergio Ricardo Ambrosio

Jairo Kenupp Bastos

Mayker Lazaro Dantas Miranda

Carlos Henrique Gomes Martins

Affiliations

Soon will be listed here.

Abstract

Aim: This paper reports on the antimycobacterial activity of the oleoresins and extracts obtained from spp.

Materials & Methods: The minimum inhibitory concentration (MIC) and fractional inhibitory concentration index techniques helped to evaluate the effect of these oleoresins and extracts against six strains of mycobacteria that cause tuberculosis.

Results & Conclusion: Among the assayed oleoresins and plant extracts, the , , and oleoresins provided the lowest MIC values against some of the tested strains. The combination of spp. samples with isoniazid did not evidence any synergistic action. Some spp. oleoresins may represent a future source for the discovery of new antimycobacterial drugs due to their low MIC values.

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