Clinical Efficacy of Photobiomodulation on Dental Implant Osseointegration: A Systematic Review

Overview

Journal Saudi J Med Med Sci

Specialty General Medicine

Date 2020 Jun 27

PMID 32587488

Citations 7

Authors

Sara Mahmoud Zayed

Ahmed Adel Abdel Hakim

Affiliations

Soon will be listed here.

Abstract

Background: Photobiomodulation (PBM) has been shown to have a positive effect on dental implant osseointegration and stability in and animal studies; however, its usefulness in dental implant clinical practice is yet unclear.

Objective: The objective was to assess the clinical effectiveness of PBM on dental implants' osseointegration.

Methods: Two reviewers independently conducted a comprehensive electronic search of articles published from inception up to January 10, 2020, in PubMed, Cochrane Library and Embase databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Randomized clinical trials (RCTs) and nonrandomized clinical studies that compared the effect of PBM on dental implant stability with control groups were included. Animals and studies studies as well as studies with confounders such as application of orthodontic were excluded. Risk of bias (using Cochrane Risk of Bias tool for RCTs and Risk of Bias in Non-Randomized Studies of Interventions tool for nonrandomized studies) was assessed by both authors. Owing to substantial heterogeneity, only a narrative synthesis of the included studies is presented.

Results: Seven relevant clinical studies were included, and they used a variety of PBM parameters and devices. The posterior region of the jaw was found to be more frequently evaluated. For assessing the effect of PBM on implant stability, five studies used resonance frequency analysis and two used periotest; three studies additionally used biomarkers for assessment. Four studies found that PBM has a potential positive effect on the outcome of dental implant stability, whereas three studies reported that PBM has no effect on implant stability.

Conclusion: The findings of this systematic review suggest that postoperative application of PBM may potentially have some positive effect on dental implant's osseointegration and stability. However, additional studies are required with uniformity in methods to provide a more robust assessment of this effect.

Citing Articles

Clinical efficacy of photobiomodulation therapy in dental implant stability and crestal bone loss in implants placed in healed sites: a systematic review and meta-analysis of randomized clinical trials.

Rani S, Dhawan P, Kruthiventi H Lasers Med Sci. 2025; 40(1):40.

PMID: 39853546 DOI: 10.1007/s10103-024-04258-x.

Potential of combined red and near-infrared photobiomodulation to mitigate pro-osteoclastic and inflammatory gene expression in human mandibular osteogenic cells.

Palmisano B, Del Vecchio A, Passaretti A, Stefano A, Miracolo G, Farinacci G Lasers Med Sci. 2024; 39(1):247.

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A novel investigational preclinical model to assess fluence rate for dental oral craniofacial tissues.

Sourvanos D, Zhu T, Dimofte A, Busch T, Lander B, Burrell J Photodiagnosis Photodyn Ther. 2024; 46:104015.

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The effect of bone remodeling with photobiomodulation in dentistry: a review study.

Mi Le J, Wu J, Jaw F, Su C Lasers Med Sci. 2023; 38(1):265.

PMID: 37973668 DOI: 10.1007/s10103-023-03933-9.

The Effect of Photobiomodulation Therapy on the Stability of Orthodontic Mini-implants in Human and Animal Studies: A Systematic Review and Meta-analysis.

Razaghi P, Moradi Haghgou J, Khazaei S, Farhadian N, Fekrazad R, Gholami L J Lasers Med Sci. 2023; 13:e27.

PMID: 36743132 PMC: 9841378. DOI: 10.34172/jlms.2022.27.

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