Serum Apelin and Galectin-3 in Preeclampsia in Iraq

Overview

Journal Hypertens Pregnancy

Publisher Informa Healthcare

Date 2020 Jun 16

PMID 32538210

Citations 16

Authors

Aamal Sattar Taha

Zohreh Zahraei

Hussein Kadhem Al-Hakeim

Affiliations

Soon will be listed here.

Abstract

Objective: This study investigates the correlation between serum apelin and galectin-3 levels with insulin resistance (IR) in women with preeclampsia (PE).

Methods: Serum apelin, galectin-3, and insulin levels were measured in 60 PE women and 30 normotensive pregnant.

Results: The PE group had significantly lower apelin and higher galectin-3 levels than the control group. PE group exhibited dyslipidemia and had higher β-cell functions than the controls. Galectin-3 level correlates with insulin, glucose, and IR. High galectin-3 also is correlated positively with dyslipidemia.

Conclusion: In PE, there is a possible contribution of galectin-3 to the harmful effects of IR and dyslipidemia.

Citing Articles

Maternal serum apelin-13 levels in early- and late-onset preeclampsia.

Gandham R, C D D, S R S Turk J Obstet Gynecol. 2024; 21(4):235-241.

PMID: 39663768 PMC: 11635722. DOI: 10.4274/tjod.galenos.2024.37657.

Bridging the Gap between Galectin-3 Expression and Hypertensive Pregnancy Disorders: A Narrative Review.

Potiris A, Fotiou A, Drakaki E, Potetsianaki A, Zikopoulos A, Moustakli E J Clin Med. 2024; 13(16).

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The Role of and Metabolic Syndrome-Related Mast Cell Activation Pathologies and Their Potential Impact on Pregnancy and Neonatal Outcomes.

Tzitiridou-Chatzopoulou M, Kazakos E, Orovou E, Andronikidi P, Kyrailidi F, Mouratidou M J Clin Med. 2024; 13(8).

PMID: 38673633 PMC: 11050948. DOI: 10.3390/jcm13082360.

Genetic Associations of Circulating Cardiovascular Proteins With Gestational Hypertension and Preeclampsia.

Schuermans A, Truong B, Ardissino M, Bhukar R, Slob E, Nakao T JAMA Cardiol. 2024; 9(3):209-220.

PMID: 38170504 PMC: 10765315. DOI: 10.1001/jamacardio.2023.4994.

The Apelinergic System in Pregnancy.

Pecheux O, Correia-Branco A, Cohen M, Martinez de Tejada B Int J Mol Sci. 2023; 24(9).

PMID: 37175743 PMC: 10178735. DOI: 10.3390/ijms24098014.