Potential Effects of Curcumin in the Treatment of COVID-19 Infection

Overview

Journal Phytother Res

Publisher Wiley

Date 2020 May 21

PMID 32430996

Citations 135

Authors

Fatemeh Zahedipour

Seyede Atefe Hosseini

Thozhukat Sathyapalan

Muhammed Majeed

Tannaz Jamialahmadi

Khalid Al-Rasadi

Maciej Banach

Amirhossein Sahebkar

Affiliations

Soon will be listed here.

Abstract

Coronavirus disease 2019 (COVID-19) outbreak is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with considerable mortality worldwide. The main clinical manifestation of COVID-19 is the presence of respiratory symptoms, but some patients develop severe cardiovascular and renal complications. There is an urgency to understand the mechanism by which this virus causes complications so as to develop treatment options. Curcumin, a natural polyphenolic compound, could be a potential treatment option for patients with coronavirus disease. In this study, we review some of the potential effects of curcumin such as inhibiting the entry of virus to the cell, inhibiting encapsulation of the virus and viral protease, as well as modulating various cellular signaling pathways. This review provides a basis for further research and development of clinical applications of curcumin for the treatment of newly emerged SARS-CoV-2.

Citing Articles

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