Effect of Structure: A New Insight into Nanoparticle Assemblies from Inanimate to Animate

Overview

Journal Sci Adv

Specialties Biology
Science

Date 2020 May 20

PMID 32426506

Citations 25

Authors

Chuanhui Huang

Xiangyu Chen

Zhenjie Xue

Tie Wang

Affiliations

Soon will be listed here.

Abstract

Nanoparticle (NP) assemblies are among the foremost achievements of nanoscience and nanotechnology because their interparticle interactions overcome the weaknesses displayed by individual NPs. However, previous studies have considered NP assemblies as inanimate, which had led to their dynamic properties being overlooked. Animate properties, i.e., those mimicking biological properties, endow NP ensembles with unique and unexpected functionalities for practical applications. In this critical review, we highlight recent advances in our understanding of the properties of NP assemblies, particularly their animate properties. Key examples are used to illustrate critical concepts, and special emphasis is placed on animate property-dependent applications. Last, we discuss the barriers to further advances in this field.

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References

Wang T, Zhuang J, Lynch J, Chen O, Wang Z, Wang X . Self-assembled colloidal superparticles from nanorods. Science. 2012; 338(6105):358-63. DOI: 10.1126/science.1224221. View

Yu L, Yang J, Guan B, Lu Y, Lou X . Hierarchical Hollow Nanoprisms Based on Ultrathin Ni-Fe Layered Double Hydroxide Nanosheets with Enhanced Electrocatalytic Activity towards Oxygen Evolution. Angew Chem Int Ed Engl. 2017; 57(1):172-176. DOI: 10.1002/anie.201710877. View

Taton T, Mirkin C, LETSINGER R . Scanometric DNA array detection with nanoparticle probes. Science. 2000; 289(5485):1757-60. DOI: 10.1126/science.289.5485.1757. View

Cheng X, Sun R, Yin L, Chai Z, Shi H, Gao M . Light-Triggered Assembly of Gold Nanoparticles for Photothermal Therapy and Photoacoustic Imaging of Tumors In Vivo. Adv Mater. 2016; 29(6). DOI: 10.1002/adma.201604894. View

Liu Y, Luo D, Wang T . Hierarchical Structures of Bone and Bioinspired Bone Tissue Engineering. Small. 2016; 12(34):4611-32. DOI: 10.1002/smll.201600626. View

Wang L, Xu L, Kuang H, Xu C, Kotov N . Dynamic nanoparticle assemblies. Acc Chem Res. 2012; 45(11):1916-26. PMC: 3479329. DOI: 10.1021/ar200305f. View

Wang Z, Liu H, Hye Yang S, Wang T, Liu C, Cao Y . Nanoparticle-based artificial RNA silencing machinery for antiviral therapy. Proc Natl Acad Sci U S A. 2012; 109(31):12387-92. PMC: 3412013. DOI: 10.1073/pnas.1207766109. View

Zhang S, Geryak R, Geldmeier J, Kim S, Tsukruk V . Synthesis, Assembly, and Applications of Hybrid Nanostructures for Biosensing. Chem Rev. 2017; 117(20):12942-13038. DOI: 10.1021/acs.chemrev.7b00088. View

Huang P, Lin J, Li W, Rong P, Wang Z, Wang S . Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy. Angew Chem Int Ed Engl. 2013; 52(52):13958-13964. PMC: 4058316. DOI: 10.1002/anie.201308986. View

10.

Ilday S, Makey G, Akguc G, Yavuz O, Tokel O, Pavlov I . Rich complex behaviour of self-assembled nanoparticles far from equilibrium. Nat Commun. 2017; 8:14942. PMC: 5414064. DOI: 10.1038/ncomms14942. View

11.

Wang Y, Peng X, Abelson A, Xiao P, Qian C, Yu L . Dynamic deformability of individual PbSe nanocrystals during superlattice phase transitions. Sci Adv. 2019; 5(6):eaaw5623. PMC: 6555630. DOI: 10.1126/sciadv.aaw5623. View

12.

Su B, Tian Y, Jiang L . Bioinspired Interfaces with Superwettability: From Materials to Chemistry. J Am Chem Soc. 2015; 138(6):1727-48. DOI: 10.1021/jacs.5b12728. View

13.

Li B, Bian K, Zhou X, Lu P, Liu S, Brener I . Pressure compression of CdSe nanoparticles into luminescent nanowires. Sci Adv. 2017; 3(5):e1602916. PMC: 5419700. DOI: 10.1126/sciadv.1602916. View

14.

Zhang C, Yan C, Xue Z, Yu W, Xie Y, Wang T . Shape-Controlled Synthesis of High-Quality Cu S Nanocrystals for Efficient Light-Induced Water Evaporation. Small. 2016; 12(38):5320-5328. DOI: 10.1002/smll.201601723. View

15.

Qin X, Luo D, Xue Z, Song Q, Wang T . Self-Assembled Ag-MXA Superclusters with Structure-Dependent Mechanical Properties. Adv Mater. 2018; 30(9). DOI: 10.1002/adma.201706327. View

16.

Teng Z, Wang C, Tang Y, Li W, Bao L, Zhang X . Deformable Hollow Periodic Mesoporous Organosilica Nanocapsules for Significantly Improved Cellular Uptake. J Am Chem Soc. 2017; 140(4):1385-1393. DOI: 10.1021/jacs.7b10694. View

17.

Song P, Qin H, Gao H, Cong H, Yu S . Self-healing and superstretchable conductors from hierarchical nanowire assemblies. Nat Commun. 2018; 9(1):2786. PMC: 6050250. DOI: 10.1038/s41467-018-05238-w. View

18.

Yan C, Wang T . A new view for nanoparticle assemblies: from crystalline to binary cooperative complementarity. Chem Soc Rev. 2017; 46(5):1483-1509. DOI: 10.1039/c6cs00696e. View

19.

Acerce M, Akdogan E, Chhowalla M . Metallic molybdenum disulfide nanosheet-based electrochemical actuators. Nature. 2017; 549(7672):370-373. DOI: 10.1038/nature23668. View

20.

Gu G, Schmid M, Chiu P, Minett A, Fraysse J, Kim G . V2O5 nanofibre sheet actuators. Nat Mater. 2003; 2(5):316-9. DOI: 10.1038/nmat880. View