» Articles » PMID: 32425315

Are We Equal in Adversity? Does Covid-19 Affect Women and Men Differently?

Overview
Journal Maturitas
Specialty Geriatrics
Date 2020 May 20
PMID 32425315
Citations 58
Authors
Affiliations
Soon will be listed here.
Abstract

Background & Objectives: This article examines whether women are less prone than men to Covid-19 infections and their complications.

Data Sources: We reviewed available databases and searched systematically for publications. To be taken into account, data had to be broken down by gender. There was no study evaluation nor quantification synthesis, due to the large heterogeneity of the studies. Nineteen databases were selected. 73 publications were considered and 33 were selected, to which 12 more were added.

Results: Globally, the proportion of men and women who tested positive is comparable. However, men are about 60 % more likely to be severely ill or to die from the complications of Covid-19 than are women.

Limitations: The study was hampered by a large heterogeneity in testing and reporting of the data.

Conclusions: Although in the pandemic men die more frequently than women from Covid-19, it is not clear whether this is due to biological differences between men and women, differences in behavioral habits, or differences in the rates of co-morbidities.

Implications Of Key Findings: Countries and studies should report their data by age, gender and co-morbidities. This may have implications in terms of vaccination strategies, the choice of treatments and future consequences for long-term health issues concerning gender equality.

Citing Articles

Should I stay (home) or should I go (party)? Examination of drinking as a mediator of the relationship between alcohol-related social media content and adherence to COVID-19 recommendations among college students.

Steers M, Wickham R, Ploykao T, Buchholz W, Tanygin A, Ward R Drug Alcohol Rev. 2024; 43(7):2055-2064.

PMID: 39269311 PMC: 11556461. DOI: 10.1111/dar.13946.


Updates in the pathophysiology of COVID-19 infection in male reproductive and sexual health: a literature review.

Alzahrani M, Alkhani K, Alassaf A, Alorainy J, Binsaleh S, Almannie R Front Endocrinol (Lausanne). 2024; 14:1226858.

PMID: 38468633 PMC: 10925715. DOI: 10.3389/fendo.2023.1226858.


Sex differences in the relationship between post-vaccination adverse reactions, decision regret, and WTP for the booster dose of COVID-19 vaccine in Taizhou, China.

Luo C, Chen H, Tung T Prev Med Rep. 2024; 37:102538.

PMID: 38162118 PMC: 10755462. DOI: 10.1016/j.pmedr.2023.102538.


SARS-CoV-2 mucosal vaccine protects against clinical disease with sex bias in efficacy.

Sui Y, Andersen H, Li J, Hoang T, Minai M, Nagata B Vaccine. 2023; 42(2):339-351.

PMID: 38071106 PMC: 10843685. DOI: 10.1016/j.vaccine.2023.11.059.


Characteristics of cases and deaths arising from SARS-CoV-2 infection in Zambia: March 2020 to April 2021.

Chanda S, Tembo E, Sinyange N, Kayeyi N, Musonda K, Chewe O Pan Afr Med J. 2023; 45:155.

PMID: 37869234 PMC: 10589408. DOI: 10.11604/pamj.2023.45.155.32018.


References
1.
Wu J, Liu J, Zhao X, Liu C, Wang W, Wang D . Clinical Characteristics of Imported Cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu Province: A Multicenter Descriptive Study. Clin Infect Dis. 2020; 71(15):706-712. PMC: 7108195. DOI: 10.1093/cid/ciaa199. View

2.
Richardson S, Hirsch J, Narasimhan M, Crawford J, McGinn T, Davidson K . Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020; 323(20):2052-2059. PMC: 7177629. DOI: 10.1001/jama.2020.6775. View

3.
Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L . Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020; 97(5):829-838. PMC: 7110296. DOI: 10.1016/j.kint.2020.03.005. View

4.
Delanghe J, Speeckaert M, De Buyzere M . COVID-19 infections are also affected by human ACE1 D/I polymorphism. Clin Chem Lab Med. 2020; 58(7):1125-1126. DOI: 10.1515/cclm-2020-0425. View

5.
Gausman J, Langer A . Sex and Gender Disparities in the COVID-19 Pandemic. J Womens Health (Larchmt). 2020; 29(4):465-466. DOI: 10.1089/jwh.2020.8472. View