COVID-19 Virus May Have Neuroinvasive Potential and Cause Neurological Complications: a Perspective Review

Overview

Journal J Neurovirol

Publisher Springer

Specialties Microbiology
Neurology

Date 2020 May 18

PMID 32418055

Citations 32

Authors

Ali Sepehrinezhad

Ali Shahbazi

Sajad Sahab Negah

Affiliations

Soon will be listed here.

Abstract

Coronavirus disease 2019 (COVID-19) was reported at the end of 2019 in China for the first time and has rapidly spread throughout the world as a pandemic. Since COVID-19 causes mild to severe acute respiratory syndrome, most studies in this field have only focused on different aspects of pathogenesis in the respiratory system. However, evidence suggests that COVID-19 may affect the central nervous system (CNS). Given the outbreak of COVID-19, it seems necessary to perform investigations on the possible neurological complications in patients who suffered from COVID-19. Here, we reviewed the evidence of the neuroinvasive potential of coronaviruses and discussed the possible pathogenic processes in CNS infection by COVID-19 to provide a precise insight for future studies.

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