» Articles » PMID: 32353398

Risk Factors for Predicting Mortality in Elderly Patients with COVID-19: A Review of Clinical Data in China

Overview
Journal Mech Ageing Dev
Specialty Geriatrics
Date 2020 May 1
PMID 32353398
Citations 111
Authors
Affiliations
Soon will be listed here.
Abstract

While elderly patients are at high risk of fatality, research concerning COVID-19 has largely been done on clarifying the clinical features. As such, the present work aims to identify risk factors for mortality in elderly patients with COVID-19. Given that single-centre studies are less likely informative as elderly remains a minority in the total Chinese population, the present study reviewed the clinical data of geriatric COVID-19 patients gathered from different sources in the public domain. Based on the data of 154 individuals from 26 provinces, age remained a key mortality risk factor among geriatric patients of different ages. While dyspnoea and chest pain/discomfort were more commonly seen in deceased patients as they represented severe pneumonia, fever was more prominent in surviving patients. This was likely due to the lower baseline body temperature observed in elderly which translated to a lower maximum temperature of fever. However, lowering the threshold temperature for fever is not recommended in surveillance. Instead, baseline body temperature measured on a regular basis should be used to define the threshold temperature for fever. Against mixed results, more research should be done on identifying comorbidities associated with mortality in geriatric patients.

Citing Articles

A longitudinal study to COVID-19 infection among university students: Physical fitness changes and psychological responses.

Hao Y, Lee J, Po Wong W, Kei Wong F, Chin Hui W, Hong Leong G J Exerc Sci Fit. 2024; 23(1):7-13.

PMID: 39697481 PMC: 11652894. DOI: 10.1016/j.jesf.2024.11.002.


Electronic health records reveal that COVID-19 impacted health resources and survival of Basque population.

Cruces-Salguero S, Larranaga I, Mar J, Matheu A Aging Clin Exp Res. 2024; 36(1):228.

PMID: 39612148 PMC: 11606984. DOI: 10.1007/s40520-024-02884-7.


Knowledge of emergency nurses and related factors toward geriatric: a cross-sectional study.

Asri A, Yeganeh Rastekanary M, Maroufizadeh S, Ghorbani Vajargah P, Karkhah S, Javadi-Pashaki N Ann Med Surg (Lond). 2024; 86(11):6477-6481.

PMID: 39525709 PMC: 11543242. DOI: 10.1097/MS9.0000000000002612.


Molecular Epidemiology of SARS-CoV-2 within Accra Metropolis Postlockdown.

Aboagye F, Annison L, Hackman H, Acquah M, Ashong Y, Owusu-Frimpong I Adv Virol. 2024; 2024:2993144.

PMID: 38584794 PMC: 10997420. DOI: 10.1155/2024/2993144.


Identification of Factors Associated with Mortality in the Elderly Population with SARS-CoV-2 Infection: Results from a Longitudinal Observational Study from Romania.

Birlutiu V, Neamtu B, Birlutiu R Pharmaceuticals (Basel). 2024; 17(2).

PMID: 38399417 PMC: 10891894. DOI: 10.3390/ph17020202.


References
1.
Obermeyer Z, Samra J, Mullainathan S . Individual differences in normal body temperature: longitudinal big data analysis of patient records. BMJ. 2017; 359:j5468. PMC: 5727437. DOI: 10.1136/bmj.j5468. View

2.
Yamamoto S, Yamazaki S, Shimizu T, Takeshima T, Fukuma S, Yamamoto Y . Body Temperature at the Emergency Department as a Predictor of Mortality in Patients With Bacterial Infection. Medicine (Baltimore). 2016; 95(21):e3628. PMC: 4902348. DOI: 10.1097/MD.0000000000003628. View

3.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z . Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229):1054-1062. PMC: 7270627. DOI: 10.1016/S0140-6736(20)30566-3. View

4.
Nicol G, Piccirillo J, Mulsant B, Lenze E . Action at a Distance: Geriatric Research during a Pandemic. J Am Geriatr Soc. 2020; 68(5):922-925. PMC: 7228241. DOI: 10.1111/jgs.16443. View

5.
Norman D . Fever in the elderly. Clin Infect Dis. 2000; 31(1):148-51. DOI: 10.1086/313896. View