» Articles » PMID: 32313813

Different Fundus Imaging Modalities and Technical Factors in AI Screening for Diabetic Retinopathy: a Review

Overview
Journal Eye Vis (Lond)
Publisher Biomed Central
Specialty Ophthalmology
Date 2020 Apr 22
PMID 32313813
Citations 21
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Effective screening is a desirable method for the early detection and successful treatment for diabetic retinopathy, and fundus photography is currently the dominant medium for retinal imaging due to its convenience and accessibility. Manual screening using fundus photographs has however involved considerable costs for patients, clinicians and national health systems, which has limited its application particularly in less-developed countries. The advent of artificial intelligence, and in particular deep learning techniques, has however raised the possibility of widespread automated screening.

Main Text: In this review, we first briefly survey major published advances in retinal analysis using artificial intelligence. We take care to separately describe standard multiple-field fundus photography, and the newer modalities of ultra-wide field photography and smartphone-based photography. Finally, we consider several machine learning concepts that have been particularly relevant to the domain and illustrate their usage with extant works.

Conclusions: In the ophthalmology field, it was demonstrated that deep learning tools for diabetic retinopathy show clinically acceptable diagnostic performance when using colour retinal fundus images. Artificial intelligence models are among the most promising solutions to tackle the burden of diabetic retinopathy management in a comprehensive manner. However, future research is crucial to assess the potential clinical deployment, evaluate the cost-effectiveness of different DL systems in clinical practice and improve clinical acceptance.

Citing Articles

A portable retina fundus photos dataset for clinical, demographic, and diabetic retinopathy prediction.

Wu C, Restrepo D, Nakayama L, Ribeiro L, Shuai Z, Barboza N Sci Data. 2025; 12(1):323.

PMID: 39987104 PMC: 11846882. DOI: 10.1038/s41597-025-04627-3.


Application and progress of artificial intelligence technology in the segmentation of hyperreflective foci in OCT images for ophthalmic disease research.

Ying J, Li H, Zhang Y, Li W, Yi Q Int J Ophthalmol. 2024; 17(6):1138-1143.

PMID: 38895690 PMC: 11144766. DOI: 10.18240/ijo.2024.06.20.


Cross-modality transfer learning with knowledge infusion for diabetic retinopathy grading.

Chen T, Bai Y, Mao H, Liu S, Xu K, Xiong Z Front Med (Lausanne). 2024; 11:1400137.

PMID: 38808141 PMC: 11130363. DOI: 10.3389/fmed.2024.1400137.


Long-Acting Microparticle Formulation of Griseofulvin for Ocular Neovascularization Therapy.

Chobisa D, Muniyandi A, Sishtla K, Corson T, Yeo Y Small. 2023; 20(10):e2306479.

PMID: 37940612 PMC: 10939919. DOI: 10.1002/smll.202306479.


Artificial Intelligence and Diabetic Retinopathy: AI Framework, Prospective Studies, Head-to-head Validation, and Cost-effectiveness.

Rajesh A, Davidson O, Lee C, Lee A Diabetes Care. 2023; 46(10):1728-1739.

PMID: 37729502 PMC: 10516248. DOI: 10.2337/dci23-0032.


References
1.
Keel S, Wu J, Lee P, Scheetz J, He M . Visualizing Deep Learning Models for the Detection of Referable Diabetic Retinopathy and Glaucoma. JAMA Ophthalmol. 2018; 137(3):288-292. PMC: 6440231. DOI: 10.1001/jamaophthalmol.2018.6035. View

2.
Lakhani P, Sundaram B . Deep Learning at Chest Radiography: Automated Classification of Pulmonary Tuberculosis by Using Convolutional Neural Networks. Radiology. 2017; 284(2):574-582. DOI: 10.1148/radiol.2017162326. View

3.
Ting D, Cheung G, Wong T . Diabetic retinopathy: global prevalence, major risk factors, screening practices and public health challenges: a review. Clin Exp Ophthalmol. 2015; 44(4):260-77. DOI: 10.1111/ceo.12696. View

4.
Kanagasingam Y, Xiao D, Vignarajan J, Preetham A, Tay-Kearney M, Mehrotra A . Evaluation of Artificial Intelligence-Based Grading of Diabetic Retinopathy in Primary Care. JAMA Netw Open. 2019; 1(5):e182665. PMC: 6324474. DOI: 10.1001/jamanetworkopen.2018.2665. View

5.
van der Heijden A, Abramoff M, Verbraak F, van Hecke M, Liem A, Nijpels G . Validation of automated screening for referable diabetic retinopathy with the IDx-DR device in the Hoorn Diabetes Care System. Acta Ophthalmol. 2017; 96(1):63-68. PMC: 5814834. DOI: 10.1111/aos.13613. View