A Case of Adult-onset Tubulointerstitial Nephritis and Uveitis Syndrome Presenting with Granulomatous Panuveitis

Overview

Journal Taiwan J Ophthalmol

Specialty Ophthalmology

Date 2020 Apr 21

PMID 32309128

Citations 1

Authors

Kemal Tekin

Yasemin Ozdamar Erol

Olcay Kurtulan

Dilek Ertoy Baydar

Affiliations

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Abstract

The tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disorder that is probably underdiagnosed in clinical practice. Ocular involvement in TINU syndrome not only presents with the nongranulomatous anterior uveitis in 80% of patients but also manifests as intermediate, posterior, or panuveitis. This case report mentions an adult male patient who presented with granulomatous iridocyclitis with panuveitis and mild renal insufficiency. Workup for connective tissue and infectious diseases was negative for the patient. He was diagnosed with TINU syndrome based on the findings of renal biopsy. Both the uveitis and nephritis promptly responded well to steroid treatment, and there was no recurrence during the follow-up of 24 months.

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PMID: 38814386 PMC: 11139823. DOI: 10.1186/s12348-024-00402-4.

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