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Acute Granulomatous Iridocyclitis in a Child with Tubulointerstitial Nephritis and Uveitis Syndrome

Overview
Journal J Ophthalmic Inflamm Infect
Publisher Springer
Specialty Ophthalmology
Date 2015 Apr 11
PMID 25861394
Citations 2
Authors
Kenan Barut
Turkay Rzayev
Nur Canpolat
Yasemin Ozluk
Ilknur Tugal-Tutkun
Ozgur Kasapcopur
Affiliations
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Abstract

Background: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness.

Findings: We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU syndrome based on renal biopsy findings. Both her uveitis and interstitial nephritis promptly responded to high-dose corticosteroid treatment, and there were no relapses during follow-up of 20 months.

Conclusions: TINU should be included in the differential diagnosis of patients who present with acute granulomatous uveitis.

Citing Articles

Tubulointerstitial nephritis and uveitis syndrome with concurrent macular edema caused by granulomatous uveitis.

Nishi T, Tamura H, Miyashita Y, Nakazato H Clin Case Rep. 2020; 8(12):2545-2549.

PMID: 33363776 PMC: 7752415. DOI: 10.1002/ccr3.3194.

A case of adult-onset tubulointerstitial nephritis and uveitis syndrome presenting with granulomatous panuveitis.

Tekin K, Ozdamar Erol Y, Kurtulan O, Baydar D Taiwan J Ophthalmol. 2020; 10(1):66-70.

PMID: 32309128 PMC: 7158930. DOI: 10.4103/tjo.tjo_33_18.

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