Enzyme Promiscuity and Evolution in Light of Cellular Metabolism
Overview
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This Special Issue is composed of 10 reviews that delve into the intricacies behind enzyme promiscuity and evolution, an area that is of increasing interest in the biological research community. In particular, the reviews in this Special Issue explore enzyme promiscuity and evolution in the context of cellular metabolism, as discussed in this introductory Editorial. It is our hope that you enjoy these fascinating and informative reviews and we wish to thank the authors for their compelling contributions to The FEBS Journal. doi: 10.1111/febs.12650.
He L, Meng F, Chen R, Qin J, Sun M, Fan Z JACS Au. 2024; 4(11):4162-4186.
PMID: 39610726 PMC: 11600172. DOI: 10.1021/jacsau.4c00849.
Primordial aminoacyl-tRNA synthetases preferred minihelices to full-length tRNA.
Tang G, Hu H, Douglas J, Carter Jr C Nucleic Acids Res. 2024; 52(12):7096-7111.
PMID: 38783009 PMC: 11229368. DOI: 10.1093/nar/gkae417.
Retracing the Rapid Evolution of an Herbicide-Degrading Enzyme by Protein Engineering.
Busch M, Drexler L, Ram Mahato D, Hiefinger C, Osuna S, Sterner R ACS Catal. 2024; 13(23):15558-15571.
PMID: 38567019 PMC: 7615792. DOI: 10.1021/acscatal.3c04010.
Selenium reduction of ubiquinone via SQOR suppresses ferroptosis.
Lee N, Park S, Lange M, Tseyang T, Doshi M, Kim T Nat Metab. 2024; 6(2):343-358.
PMID: 38351124 PMC: 11694790. DOI: 10.1038/s42255-024-00974-4.
Enzyme function and evolution through the lens of bioinformatics.
Ribeiro A, Riziotis I, Borkakoti N, Thornton J Biochem J. 2023; 480(22):1845-1863.
PMID: 37991346 PMC: 10754289. DOI: 10.1042/BCJ20220405.