Parahydrogen-Induced Radio Amplification by Stimulated Emission of Radiation

Overview

Journal Angew Chem Int Ed Engl

Specialty Chemistry

Date 2020 Mar 25

PMID 32207871

Citations 18

Authors

Baptiste Joalland

Nuwandi M Ariyasingha

Soren Lehmkuhl

Thomas Theis

Stephan Appelt

Eduard Y Chekmenev

Affiliations

Soon will be listed here.

Abstract

Radio amplification by stimulated emission of radiation (RASER) was recently discovered in a low-field NMR spectrometer incorporating a highly specialized radio-frequency resonator, where a high degree of proton-spin polarization was achieved by reversible parahydrogen exchange. RASER activity, which results from the coherent coupling between the nuclear spins and the inductive detector, can overcome the limits of frequency resolution in NMR. Here we show that this phenomenon is not limited to low magnetic fields or the use of resonators with high-quality factors. We use a commercial bench-top 1.4 T NMR spectrometer in conjunction with pairwise parahydrogen addition producing proton-hyperpolarized molecules in the Earth's magnetic field (ALTADENA condition) or in a high magnetic field (PASADENA condition) to induce RASER without any radio-frequency excitation pulses. The results demonstrate that RASER activity can be observed on virtually any NMR spectrometer and measures most of the important NMR parameters with high precision.

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