An Observational Study of Social Interaction Skills and Behaviors in Cornelia De Lange, Fragile X and Rubinstein-Taybi Syndromes

Overview

Journal J Autism Dev Disord

Publisher Springer

Date 2020 Mar 20

PMID 32189229

Citations 8

Authors

Katherine Ellis

Chris Oliver

Chrysi Stefanidou

Ian Apperly

Jo Moss

Affiliations

Soon will be listed here.

Abstract

We directly assessed the broader aspects of sociability (social enjoyment, social motivation, social interaction skills and social discomfort) in individuals with Cornelia de Lange (CdLS), fragile X (FXS) and Rubinstein-Taybi syndromes (RTS), and their association with autism characteristics and chronological age in these groups. Individuals with FXS (p < 0.01) and RTS (p < 0.01) showed poorer quality of eye contact compared to individuals with CdLS. Individuals with FXS showed less person and more object attention than individuals with CdLS (p < 0.01). Associations between sociability and autism characteristics and chronological age differed between groups, which may indicate divergence in the development and aetiology of different components of sociability across these groups. Findings indicate that individuals with CdLS, FXS and RTS show unique profiles of sociability.

Citing Articles

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Assessment of Quality of Life Using the Kidslife Scale in Individuals With Cornelia de Lange Syndrome.

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Behavioral and neuropsychiatric challenges across the lifespan in individuals with Rubinstein-Taybi syndrome.

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Age-Dependent Dysregulation of APP in Neuronal and Skin Cells from Fragile X Individuals.

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