Bioinspired Structural Color Patch with Anisotropic Surface Adhesion

Overview

Journal Sci Adv

Specialties Biology
Science

Date 2020 Feb 12

PMID 32042897

Citations 43

Authors

Yu Wang

Luoran Shang

Guopu Chen

Lingyu Sun

Xiaoxuan Zhang

Yuanjin Zhao

Affiliations

Soon will be listed here.

Abstract

Patch plays an important role in clinical medicine for its broad applications in tissue repair and regeneration. Here, inspired by the diverse adhesion, anti-adhesion, and responsive structural color phenomena in biological interfaces, we present a hybrid hydrogel film with an adhesive polydopamine (PDA) layer and an anti-adhesive poly(ethylene glycol) diacrylate (PEGDA) layer in an inverse opal scaffold. It was demonstrated that the resultant hydrogel film could serve as a functional tissue patch with an excellent adhesion property on one surface for repairing injured tissues and an anti-adhesion property on the other surface for preventing adverse adhesion. Besides, because of the responsive structural color, the patch was imparted with self-reporting mechanical capability, which could provide a real-time color-sensing feedback to monitor the heartbeat activity. Moreover, the catechol groups on PDA imparted the patch with high tissue adhesiveness and self-healing capability in vivo. These features give the bioinspired patch high potential in biomedical applications.

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