Carnitine Acetyltransferase: Candidate for the Transfer of Acetyl Groups Through the Mitochondrial Membrane of Yeast

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1977 Feb 1

PMID 320182

Citations 16

Authors

G B Kohlhaw

Affiliations

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Abstract

On the basis of its specific activity and its affinity for acetyl-coenzyme A, carnitine acetyltransferase appears to be the most likely candidate for acetyl group transfer out of yeast mitochondria.

Citing Articles

Hyperpolarized [1-C]Acetyl-l-Carnitine Probes Tricarboxylic Acid Cycle Activity .

Chen J, Singh T, Al Nemri S, Zaidi M, Billingsley K, Park J ACS Sens. 2023; 8(8):2927-2932.

PMID: 37578472 PMC: 11227661. DOI: 10.1021/acssensors.3c01046.

Requirements for Carnitine Shuttle-Mediated Translocation of Mitochondrial Acetyl Moieties to the Yeast Cytosol.

van Rossum H, Kozak B, Niemeijer M, Dykstra J, Luttik M, Daran J mBio. 2016; 7(3).

PMID: 27143389 PMC: 4959659. DOI: 10.1128/mBio.00520-16.

Alternative reactions at the interface of glycolysis and citric acid cycle in Saccharomyces cerevisiae.

van Rossum H, Kozak B, Niemeijer M, Duine H, Luttik M, Boer V FEMS Yeast Res. 2016; 16(3).

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Metabolic networks and bioenergetics of Aurantiochytrium sp. B-072 during storage lipid formation.

Chaisawang M, Verduyn C, Chauvatcharin S, Suphantharika M Braz J Microbiol. 2013; 43(3):1192-205.

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Mitochondrial carnitine-dependent acetyl coenzyme A transport is required for normal sexual and asexual development of the ascomycete Gibberella zeae.

Son H, Min K, Lee J, Choi G, Kim J, Lee Y Eukaryot Cell. 2012; 11(9):1143-53.

PMID: 22798392 PMC: 3445975. DOI: 10.1128/EC.00104-12.

References

Polakis E, Bartley W . Changes in the enzyme activities of Saccharomyces cerevisiae during aerobic growth on different carbon sources. Biochem J. 1965; 97(1):284-97. PMC: 1264573. DOI: 10.1042/bj0970284. View

Fritz I . CARNITINE AND ITS ROLE IN FATTY ACID METABOLISM. Adv Lipid Res. 1963; 1:285-334. View

Holzer H . Regulation of carbohydrate metabolism by enzyme competition. Cold Spring Harb Symp Quant Biol. 1961; 26:277-88. DOI: 10.1101/sqb.1961.026.01.034. View

Eaton N, Klein H . Studies on the aerobic degradation of glucose by Saccharomyces cerevisiae. Biochem J. 1957; 67(3):373-81. PMC: 1200167. DOI: 10.1042/bj0670373. View

SRERE P . The citrate enzymes: their structures, mechanisms, and biological functions. Curr Top Cell Regul. 1972; 5:229-83. DOI: 10.1016/b978-0-12-152805-8.50013-7. View