Heart and Anorexia Nervosa

Overview

Journal Heart Fail Rev

Date 2019 Dec 25

PMID 31873842

Citations 5

Authors

Abdallah Fayssoil

Jean Claude Melchior

Mouna Hanachi

Affiliations

Soon will be listed here.

Abstract

Anorexia nervosa, one of the more frequent and severe eating disorders, is a chronic psychiatric disease with potentially serious somatic consequences. This behavioral symptomatology leads to weight loss, undernutrition, and more or less severe-potentially life-threatening-somatic complications including respiratory, hepatic, digestive and cardiac features, electrolyte disturbances, endocrine and bone impairment, immunodepression, and related opportunistic infections. In this review, the authors report an overview of cardiac diseases in this disease.

Citing Articles

Cardiological Aspects of Feeding and Eating Disorders in Children and Adolescents and Associations with Refeeding Syndrome, Purging Behaviors, and Psychoactive Drugs.

Letizia C, Pruccoli J, Pannacci U, Napolitano T, Fabi M, Parmeggiani A J Cardiovasc Dev Dis. 2025; 12(2).

PMID: 39997500 PMC: 11856957. DOI: 10.3390/jcdd12020066.

Patterns of Medical Diagnoses Before and After a Diagnosis of Anorexia Nervosa: A Danish Nationwide Cohort Study.

Soeby M, Clausen L, Richelsen B, Gribsholt S Int J Eat Disord. 2025; 58(3):624-634.

PMID: 39763082 PMC: 11891635. DOI: 10.1002/eat.24340.

Incidence and Risk of Cardiovascular Outcomes in Patients With Anorexia Nervosa.

Tseng M, Chiou K, Shao J, Liu H JAMA Netw Open. 2024; 7(12):e2451094.

PMID: 39699895 PMC: 11659916. DOI: 10.1001/jamanetworkopen.2024.51094.

Effects of autism on 30-year outcome of anorexia nervosa.

Nielsen S, Dobrescu S, Dinkler L, Gillberg C, Gillberg C, Rastam M J Eat Disord. 2022; 10(1):4.

PMID: 35000620 PMC: 8744255. DOI: 10.1186/s40337-021-00518-1.

Global and Regional Myocardial Work in Female Adolescents with Weight Disorders.

Paysal J, Merlin E, Rochette E, Terral D, Nottin S J Clin Med. 2021; 10(20).

PMID: 34682793 PMC: 8537237. DOI: 10.3390/jcm10204671.

References

Herzog W, Deter H, Fiehn W, PETZOLD E . Medical findings and predictors of long-term physical outcome in anorexia nervosa: a prospective, 12-year follow-up study. Psychol Med. 1997; 27(2):269-79. DOI: 10.1017/s0033291796004394. View

Miller K, Grinspoon S, Ciampa J, Hier J, Herzog D, Klibanski A . Medical findings in outpatients with anorexia nervosa. Arch Intern Med. 2005; 165(5):561-6. DOI: 10.1001/archinte.165.5.561. View

De Simone G, Scalfi L, Galderisi M, Celentano A, Di Biase G, Tammaro P . Cardiac abnormalities in young women with anorexia nervosa. Br Heart J. 1994; 71(3):287-92. PMC: 483668. DOI: 10.1136/hrt.71.3.287. View

Goldberg S, Comerci G, Feldman L . Cardiac output and regional myocardial contraction in anorexia nervosa. J Adolesc Health Care. 1988; 9(1):15-21. DOI: 10.1016/0197-0070(88)90013-7. View

Morris R, Prasad A, Asaro J, Guzman M, Sanders L, Hauck A . Markers of Cardiovascular Dysfunction in Adolescents With Anorexia Nervosa. Glob Pediatr Health. 2017; 4:2333794X17727423. PMC: 5580842. DOI: 10.1177/2333794X17727423. View

Casiero D, Frishman W . Cardiovascular complications of eating disorders. Cardiol Rev. 2006; 14(5):227-31. DOI: 10.1097/01.crd.0000216745.96062.7c. View

Di Cola G, Jacoangeli F, Jacoangeli F, Lombardo M, Iellamo F . Cardiovascular disorders in anorexia nervosa and potential therapeutic targets. Intern Emerg Med. 2014; 9(7):717-21. DOI: 10.1007/s11739-014-1107-2. View

Olivares J, Vazquez M, Fleta J, Moreno L, Perez-Gonzalez J, Bueno M . Cardiac findings in adolescents with anorexia nervosa at diagnosis and after weight restoration. Eur J Pediatr. 2005; 164(6):383-6. DOI: 10.1007/s00431-005-1647-6. View

Sachs K, Harnke B, Mehler P, Krantz M . Cardiovascular complications of anorexia nervosa: A systematic review. Int J Eat Disord. 2015; 49(3):238-48. DOI: 10.1002/eat.22481. View

10.

Takahashi S, Mine T . An Endomyocardial Biopsy of the Left Ventricle in an Anorexia Nervosa Patient with Sinus Bradycardia and Left Ventricular Systolic Dysfunction. Case Rep Cardiol. 2016; 2016:9805291. PMC: 5090078. DOI: 10.1155/2016/9805291. View

11.

Romano C, Chinali M, Pasanisi F, Greco R, Celentano A, Rocco A . Reduced hemodynamic load and cardiac hypotrophy in patients with anorexia nervosa. Am J Clin Nutr. 2003; 77(2):308-12. DOI: 10.1093/ajcn/77.2.308. View

12.

Palla B, Litt I . Medical complications of eating disorders in adolescents. Pediatrics. 1988; 81(5):613-23. View

13.

Galetta F, Franzoni F, Prattichizzo F, Rolla M, Santoro G, Pentimone F . Heart rate variability and left ventricular diastolic function in anorexia nervosa. J Adolesc Health. 2003; 32(6):416-21. DOI: 10.1016/s1054-139x(03)00048-x. View

14.

Thurston J, Marks P . Electrocardiographic abnormalities in patients with anorexia nervosa. Br Heart J. 1974; 36(7):719-23. PMC: 458886. DOI: 10.1136/hrt.36.7.719. View

15.

Krantz M, Sabel A, Sagar U, Long C, Barbey J, White K . Factors influencing QT prolongation in patients hospitalized with severe anorexia nervosa. Gen Hosp Psychiatry. 2011; 34(2):173-7. DOI: 10.1016/j.genhosppsych.2011.08.003. View

16.

Dec G, Biederman J, Hougen T . Cardiovascular findings in adolescent inpatients with anorexia nervosa. Psychosom Med. 1987; 49(3):285-90. DOI: 10.1097/00006842-198705000-00007. View

17.

Nudel D, GOOTMAN N, Nussbaum M, Shenker I . Altered exercise performance and abnormal sympathetic responses to exercise in patients with anorexia nervosa. J Pediatr. 1984; 105(1):34-7. DOI: 10.1016/s0022-3476(84)80352-2. View

18.

Kollai M, Bonyhay I, Jokkel G, Szonyi L . Cardiac vagal hyperactivity in adolescent anorexia nervosa. Eur Heart J. 1994; 15(8):1113-8. DOI: 10.1093/oxfordjournals.eurheartj.a060636. View

19.

Kanbur N, Goldberg E, Pinhas L, Hamilton R, Clegg R, Katzman D . Second-degree atrioventricular block (Mobitz Type I) in an adolescent with anorexia nervosa: intrinsic or acquired conduction abnormality. Int J Eat Disord. 2009; 42(6):575-8. DOI: 10.1002/eat.20647. View

20.

Bravender T, Kanter R, Zucker N . Anorexia nervosa and second-degree atrioventricular block (Type I). Int J Eat Disord. 2006; 39(7):612-5. DOI: 10.1002/eat.20235. View