Cell Membrane Localization of Sterols with Conventional and Unusual Side Chains in Two Marine Demosponges

Overview

Journal Lipids

Specialty Biochemistry

Date 1988 Aug 1

PMID 3185106

Citations 7

Authors

M P Lawson

I L Stoilov

J E Thompson

C Djerassi

Affiliations

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Abstract

Subcellular fractionation by differential centrifugation was performed on two previously unstudied marine sponges that predominantly contain either conventional (Reniera sp.) or unconventional (Pseudaxinyssa sp.) sterols. Direct evidence for the presence of unconventional sterols with C24 alkylated side chains in the cellular membranes of Pseudaxinyssa sp. is provided, but the presence of unconventional sterols in sponge membranes is shown not to be a universal feature of the Porifera. Possible structural and functional roles of unconventional lipid molecules in sponge cell membranes are discussed.

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Cell membrane localization of long chain C24-C30 fatty acids in two marine demosponges.

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