Ischemic Preconditioning Has No Effect on Maximal Arm Cycling Exercise in Women

Overview

Journal Eur J Appl Physiol

Specialty Physiology

Date 2019 Dec 9

PMID 31813045

Citations 11

Authors

Gustavo R Mota

Zachary B Rightmire

Jeffrey S Martin

James R McDonald

Andreas N Kavazis

David D Pascoe

L Bruce Gladden

Affiliations

Soon will be listed here.

Abstract

Purpose: We investigated the effect of ischemic preconditioning (IPC) on performance of a 3 min maximal effort arm ergometer test in young women.

Methods: Twenty healthy women (23.1 (SD 3.3) years) performed a 3 min maximal effort arm cycling exercise, preceded by IPC on both arms or SHAM in a counterbalanced randomized crossover design. Both blood flow (via high resolution ultrasound; n = 17) and muscle oxygenation/deoxygenation (via near infrared spectroscopy; n = 5) were measured throughout the IPC/SHAM. Performance and perceptual/physiological (i.e., heart rate, blood lactate, rating of perceived exertion, and triceps brachialis oxygenation) parameters were recorded during the exercise test.

Results: Occlusion during IPC completely blocked brachial artery blood flow, decreased oxygenated hemoglobin/myoglobin (Δ[oxy(Hb + Mb)]), and increased deoxygenated Hb/Mb (Δ[deoxy(Hb + Mb)]). There were no differences (P > 0.797) in performance (peak, mean, and end power output) or in any perceptual/physiological variables during the 3 min all-out test between IPC/SHAM. During exercise, Δ[oxy(Hb + Mb)] initially decreased with no differences (P ≥ 0.296) between conditions and returned towards baseline by the completion of the test while Δ[deoxy(Hb + Mb)] increased with no differences between conditions and remained elevated until completion of the test (P ≥ 0.755).

Conclusions: We verified the successful application of IPC via blood flow and NIRS measures but found no effects on performance of a 3 min maximal effort arm cranking test in young women.

Citing Articles

Evaluating Local Muscle Oxygen Saturation: Ischemic Preconditioning Protocols and the Myth of Overcompensation.

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Does ischemic preconditioning enhance sports performance more than placebo or no intervention? A systematic review with meta-analysis.

Souza H, Oliveira G, Meireles A, Dos Santos M, Vieira J, Arriel R J Sport Health Sci. 2024; 14:101010.

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Muscle Oximetry in Sports Science: An Updated Systematic Review.

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Effects of remote ischemic conditioning on conditioned pain modulation and cardiac autonomic modulation in women with knee osteoarthritis: placebo-controlled randomized clinical trial protocol.

Biral T, Cavina A, Junior E, Teixeira Filho C, Vanderlei F Trials. 2023; 24(1):502.

PMID: 37550703 PMC: 10405415. DOI: 10.1186/s13063-023-07527-2.

Ischemic Preconditioning Improves the Bench-Press Maximal Strength in Resistance-Trained Men.

Rodrigues A, Ide B, Sasaki J, DE Oliveira D, DE Oliveira Assumpcao C, Marocolo M Int J Exerc Sci. 2023; 16(4):217-229.

PMID: 37113512 PMC: 10124736. DOI: 10.70252/JLBH8684.

References

Murry C, Jennings R, Reimer K . Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986; 74(5):1124-36. DOI: 10.1161/01.cir.74.5.1124. View

Beaven C, Cook C, Kilduff L, Drawer S, Gill N . Intermittent lower-limb occlusion enhances recovery after strenuous exercise. Appl Physiol Nutr Metab. 2012; 37(6):1132-9. DOI: 10.1139/h2012-101. View

Marocolo I, Ribeiro da Mota G, Londe A, Patterson S, Barbosa Neto O, Marocolo M . Acute ischemic preconditioning does not influence high-intensity intermittent exercise performance. PeerJ. 2017; 5:e4118. PMC: 5712465. DOI: 10.7717/peerj.4118. View

Kjeld T, Rasmussen M, Jattu T, Nielsen H, Secher N . Ischemic preconditioning of one forearm enhances static and dynamic apnea. Med Sci Sports Exerc. 2013; 46(1):151-5. DOI: 10.1249/MSS.0b013e3182a4090a. View

Ferreira T, Sabino-Carvalho J, Lopes T, Ribeiro I, Succi J, da Silva A . Ischemic Preconditioning and Repeated Sprint Swimming: A Placebo and Nocebo Study. Med Sci Sports Exerc. 2016; 48(10):1967-75. DOI: 10.1249/MSS.0000000000000977. View

Martin J, Borges A, Christy 4th J, Beck D . Considerations for SphygmoCor radial artery pulse wave analysis: side selection and peripheral arterial blood pressure calibration. Hypertens Res. 2015; 38(10):675-83. DOI: 10.1038/hr.2015.36. View

Sabino-Carvalho J, Lopes T, Obeid-Freitas T, Ferreira T, Succi J, Silva A . Effect of Ischemic Preconditioning on Endurance Performance Does Not Surpass Placebo. Med Sci Sports Exerc. 2016; 49(1):124-132. DOI: 10.1249/MSS.0000000000001088. View

Brown H, Binnie M, Dawson B, Bullock N, Scott B, Peeling P . Factors affecting occlusion pressure and ischemic preconditioning. Eur J Sport Sci. 2018; 18(3):387-396. DOI: 10.1080/17461391.2017.1421712. View

Marocolo M, da Mota G, Simim M, Coriolano H . Myths and Facts About the Effects of Ischemic Preconditioning on Performance. Int J Sports Med. 2015; 37(2):87-96. DOI: 10.1055/s-0035-1564253. View

10.

Arriel R, de Souza H, Ribeiro da Mota G, Marocolo M . Declines in exercise performance are prevented 24 hours after post-exercise ischemic conditioning in amateur cyclists. PLoS One. 2018; 13(11):e0207053. PMC: 6226188. DOI: 10.1371/journal.pone.0207053. View

11.

Sharma V, Cunniffe B, Verma A, Cardinale M, Yellon D . Characterization of acute ischemia-related physiological responses associated with remote ischemic preconditioning: a randomized controlled, crossover human study. Physiol Rep. 2014; 2(11). PMC: 4255807. DOI: 10.14814/phy2.12200. View

12.

Marocolo M, Marocolo I, da Mota G, Simao R, Maior A, Coriolano H . Beneficial Effects of Ischemic Preconditioning in Resistance Exercise Fade Over Time. Int J Sports Med. 2016; 37(10):819-24. DOI: 10.1055/s-0042-109066. View

13.

Laurent C, Green J, Bishop P, Sjokvist J, Schumacker R, Richardson M . A practical approach to monitoring recovery: development of a perceived recovery status scale. J Strength Cond Res. 2010; 25(3):620-8. DOI: 10.1519/JSC.0b013e3181c69ec6. View

14.

Incognito A, Burr J, Millar P . The Effects of Ischemic Preconditioning on Human Exercise Performance. Sports Med. 2015; 46(4):531-44. DOI: 10.1007/s40279-015-0433-5. View

15.

Erickson M, Ryan T, Young H, McCully K . Near-infrared assessments of skeletal muscle oxidative capacity in persons with spinal cord injury. Eur J Appl Physiol. 2013; 113(9):2275-83. PMC: 3754783. DOI: 10.1007/s00421-013-2657-0. View

16.

Ghosh S, Standen N, Galinanes M . Preconditioning the human myocardium by simulated ischemia: studies on the early and delayed protection. Cardiovasc Res. 2000; 45(2):339-50. DOI: 10.1016/s0008-6363(99)00353-3. View

17.

Bailey T, Birk G, Cable N, Atkinson G, Green D, Jones H . Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise. Am J Physiol Heart Circ Physiol. 2012; 303(5):H533-8. DOI: 10.1152/ajpheart.00272.2012. View

18.

Lalonde F, Curnier D . Can anaerobic performance be improved by remote ischemic preconditioning?. J Strength Cond Res. 2014; 29(1):80-5. DOI: 10.1519/JSC.0000000000000609. View

19.

Marocolo M, da Mota G, Pelegrini V, Appell Coriolano H . Are the Beneficial Effects of Ischemic Preconditioning on Performance Partly a Placebo Effect?. Int J Sports Med. 2015; 36(10):822-5. DOI: 10.1055/s-0035-1549857. View

20.

Hunter S . The Relevance of Sex Differences in Performance Fatigability. Med Sci Sports Exerc. 2016; 48(11):2247-2256. PMC: 5349856. DOI: 10.1249/MSS.0000000000000928. View