Advancements to the Axolotl Model for Regeneration and Aging

Overview

Journal Gerontology

Specialty Geriatrics

Date 2019 Nov 29

PMID 31779024

Citations 24

Authors

Warren A Vieira

Kaylee M Wells

Catherine D McCusker

Affiliations

Soon will be listed here.

Abstract

Loss of regenerative capacity is a normal part of aging. However, some organisms, such as the Mexican axolotl, retain striking regenerative capacity throughout their lives. Moreover, the development of age-related diseases is rare in this organism. In this review, we will explore how axolotls are used as a model system to study regenerative processes, the exciting new technological advancements now available for this model, and how we can apply the lessons we learn from studying regeneration in the axolotl to understand, and potentially treat, age-related decline in humans.

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