State-level Estimates of Excess Hospitalizations and Deaths Associated with Influenza

Overview

Journal Influenza Other Respir Viruses

Publisher Wiley

Specialty Microbiology

Date 2019 Nov 9

PMID 31702114

Citations 9

Authors

Christopher A Czaja

Lisa Miller

Kathryn Colborn

Myles G Cockburn

Nisha Alden

Rachel K Herlihy

Eric A F Simoes

Affiliations

Soon will be listed here.

Abstract

Background: National estimates of influenza burden may not reflect state-level influenza activity, and local surveillance may not capture the full burden of influenza.

Methods: To provide state-level information about influenza burden, we estimated excess pneumonia and influenza (P&I) and respiratory and circulatory (R&C) hospitalizations and deaths in Colorado from local hospital discharge records, death certificates, and influenza virus surveillance using negative binomial models.

Results: From July 2007 to June 2016, influenza was associated with an excess of 17 911 P&I hospitalizations (95%CI: 15 227, 20 354), 30 811 R&C hospitalizations (95%CI: 24 344, 37 176), 1,064 P&I deaths (95%CI: 757, 1298), and 3828 R&C deaths (95%CI: 2060, 5433). There was a large burden of influenza A(H1N1) among persons aged 0-64 years, with high median seasonal rates of excess hospitalization among persons aged 0-4 years. Persons aged ≥65 years experienced the largest numbers and highest median seasonal rates of excess hospitalization and death associated with influenza A (H3N2). The burden of influenza B was generally lower, with elevated median seasonal rates of excess hospitalization among persons aged 0-4 years and ≥65 years.

Conclusions: These findings complement existing influenza surveillance. Periodic state-level estimates of influenza disease burden may be useful for setting state public health priorities and planning prevention and control initiatives.

Citing Articles

Construction and validation of a covariate-based model for district-level estimation of excess deaths due to COVID-19 in India.

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Uncovering the burden of Influenza in children in Portugal, 2008-2018.

Afonso A, Gouveia C, Januario G, Carmo M, Lopes H, Bricout H BMC Infect Dis. 2024; 24(1):100.

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Excess hospitalizations and mortality associated with seasonal influenza in Spain, 2008-2018.

Pumarola T, Diez-Domingo J, Martinon-Torres F, Redondo Marguello E, de Lejarazu Leonardo R, Carmo M BMC Infect Dis. 2023; 23(1):86.

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Froes F, Carmo M, Lopes H, Bizouard G, Gomes C, Martins M BMC Infect Dis. 2022; 22(1):726.

PMID: 36071375 PMC: 9450401. DOI: 10.1186/s12879-022-07713-8.

Estimating the burden of influenza-related and associated hospitalizations and deaths in France: An eight-season data study, 2010-2018.

Lemaitre M, Fouad F, Carrat F, Crepey P, Gaillat J, Gavazzi G Influenza Other Respir Viruses. 2022; 16(4):717-725.

PMID: 35014194 PMC: 9178052. DOI: 10.1111/irv.12962.

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