The New International Neuroblastoma Response Criteria

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2019 Oct 18

PMID 31620844

Citations 12

Authors

Katharine E Orr

Kieran McHugh

Affiliations

Soon will be listed here.

Abstract

Over recent years significant advances in histopathology and functional imaging techniques for the diagnosis and restaging of children with neuroblastoma have led to better quantification of disease and assessment of disease response, allowing for better treatment stratification. In this review we summarise recent changes to the International Neuroblastoma Response Criteria including the use of RECIST (Response Evaluation Criteria in Solid Tumours) guidance for measurable soft-tissue disease, replacement of technetium-99 m-methylene diphosphonate (MDP) bone scans with metaiodobenzylguanidine (MIBG) scan or [F-18]2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET)/CT scanning, and a new category of minimal residual bone marrow disease.

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References

Park J, Bagatell R, Cohn S, Pearson A, Villablanca J, Berthold F . Revisions to the International Neuroblastoma Response Criteria: A Consensus Statement From the National Cancer Institute Clinical Trials Planning Meeting. J Clin Oncol. 2017; 35(22):2580-2587. PMC: 5676955. DOI: 10.1200/JCO.2016.72.0177. View

Lewington V, Lambert B, Poetschger U, Sever Z, Giammarile F, McEwan A . I-mIBG scintigraphy in neuroblastoma: development of a SIOPEN semi-quantitative reporting ,method by an international panel. Eur J Nucl Med Mol Imaging. 2016; 44(2):234-241. PMC: 5214990. DOI: 10.1007/s00259-016-3516-0. View

Bagatell R, McHugh K, Naranjo A, Van Ryn C, Kirby C, Brock P . Assessment of Primary Site Response in Children With High-Risk Neuroblastoma: An International Multicenter Study. J Clin Oncol. 2016; 34(7):740-6. PMC: 4872026. DOI: 10.1200/JCO.2015.63.2042. View

Monclair T, Brodeur G, Ambros P, Brisse H, Cecchetto G, Holmes K . The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol. 2008; 27(2):298-303. PMC: 2650389. DOI: 10.1200/JCO.2008.16.6876. View

Bar-Sever Z, Biassoni L, Shulkin B, Kong G, Hofman M, Lopci E . Guidelines on nuclear medicine imaging in neuroblastoma. Eur J Nucl Med Mol Imaging. 2018; 45(11):2009-2024. DOI: 10.1007/s00259-018-4070-8. View

Brodeur G, Seeger R, Barrett A, Berthold F, Castleberry R, DAngio G . International criteria for diagnosis, staging, and response to treatment in patients with neuroblastoma. J Clin Oncol. 1988; 6(12):1874-81. DOI: 10.1200/JCO.1988.6.12.1874. View

Sundell I, Hallmans G, Nilsson T, Nygren C . Plasma glucose and insulin, urinary catecholamine and cortisol responses to test breakfasts with high or low fibre content: the importance of the previous diet. Ann Nutr Metab. 1989; 33(6):333-40. DOI: 10.1159/000177555. View

Cecchetto G, Mosseri V, De Bernardi B, Helardot P, Monclair T, Costa E . Surgical risk factors in primary surgery for localized neuroblastoma: the LNESG1 study of the European International Society of Pediatric Oncology Neuroblastoma Group. J Clin Oncol. 2005; 23(33):8483-9. DOI: 10.1200/JCO.2005.02.4661. View

Mueller W, Coppenrath E, Pfluger T . Nuclear medicine and multimodality imaging of pediatric neuroblastoma. Pediatr Radiol. 2012; 43(4):418-27. DOI: 10.1007/s00247-012-2512-1. View

10.

Goo H . Whole-body MRI of neuroblastoma. Eur J Radiol. 2009; 75(3):306-14. DOI: 10.1016/j.ejrad.2009.09.014. View

11.

Yanik G, Parisi M, Shulkin B, Naranjo A, Kreissman S, London W . Semiquantitative mIBG scoring as a prognostic indicator in patients with stage 4 neuroblastoma: a report from the Children's oncology group. J Nucl Med. 2013; 54(4):541-8. PMC: 5503147. DOI: 10.2967/jnumed.112.112334. View

12.

Weetman R, Rider P, Oei T, Hempel J, Baehner R . Effect of diet on urinary excretion of VMA, HVA, metanephrine, and total free catecholamine in normal preschool children. J Pediatr. 1976; 88(1):46-50. DOI: 10.1016/s0022-3476(76)80725-1. View

13.

Brodeur G, Pritchard J, Berthold F, Carlsen N, Castel V, Castelberry R . Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol. 1993; 11(8):1466-77. DOI: 10.1200/JCO.1993.11.8.1466. View

14.

Brisse H, McCarville M, Granata C, Krug K, Wootton-Gorges S, Kanegawa K . Guidelines for imaging and staging of neuroblastic tumors: consensus report from the International Neuroblastoma Risk Group Project. Radiology. 2011; 261(1):243-57. DOI: 10.1148/radiol.11101352. View