Effect of Pediatric Influenza Vaccination on Antibiotic Resistance, England and Wales

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2019 Oct 2

PMID 31574242

Citations 4

Authors

Chungman Chae

Nicholas G Davies

Mark Jit

Katherine E Atkins

Affiliations

Soon will be listed here.

Abstract

Vaccines against viral infections have been proposed to reduce prescribing of antibiotics and thereby help control resistant bacterial infections. However, by combining published data sources, we predict that pediatric live attenuated influenza vaccination in England and Wales will not substantially reduce antibiotic consumption or adverse health outcomes associated with antibiotic resistance.

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References

Smieszek T, Pouwels K, Dolk F, Smith D, Hopkins S, Sharland M . Potential for reducing inappropriate antibiotic prescribing in English primary care. J Antimicrob Chemother. 2018; 73(suppl_2):ii36-ii43. PMC: 5890667. DOI: 10.1093/jac/dkx500. View

Shrestha P, Cooper B, Coast J, Oppong R, Do Thi Thuy N, Phodha T . Enumerating the economic cost of antimicrobial resistance per antibiotic consumed to inform the evaluation of interventions affecting their use. Antimicrob Resist Infect Control. 2018; 7:98. PMC: 6085682. DOI: 10.1186/s13756-018-0384-3. View

Curtis H, Walker A, Mahtani K, Goldacre B . Time trends and geographical variation in prescribing of antibiotics in England 1998-2017. J Antimicrob Chemother. 2018; 74(1):242-250. DOI: 10.1093/jac/dky377. View

de Kraker M, Jarlier V, Monen J, Heuer O, van de Sande N, Grundmann H . The changing epidemiology of bacteraemias in Europe: trends from the European Antimicrobial Resistance Surveillance System. Clin Microbiol Infect. 2012; 19(9):860-8. DOI: 10.1111/1469-0691.12028. View

Pouwels K, Dolk F, Smith D, Robotham J, Smieszek T . Actual versus 'ideal' antibiotic prescribing for common conditions in English primary care. J Antimicrob Chemother. 2018; 73(suppl_2):19-26. PMC: 5890776. DOI: 10.1093/jac/dkx502. View

Cromer D, van Hoek A, Jit M, Edmunds W, Fleming D, Miller E . The burden of influenza in England by age and clinical risk group: a statistical analysis to inform vaccine policy. J Infect. 2013; 68(4):363-71. DOI: 10.1016/j.jinf.2013.11.013. View

Atkins K, Lafferty E, Deeny S, Davies N, Robotham J, Jit M . Use of mathematical modelling to assess the impact of vaccines on antibiotic resistance. Lancet Infect Dis. 2017; 18(6):e204-e213. DOI: 10.1016/S1473-3099(17)30478-4. View

Muller-Pebody B, Sinnathamby M, Warburton F, Rooney G, Andrews N, Whitaker H . Impact of the childhood influenza vaccine programme on antibiotic prescribing rates in primary care in England. Vaccine. 2021; 39(45):6622-6627. DOI: 10.1016/j.vaccine.2021.09.069. View

Baguelin M, Camacho A, Flasche S, Edmunds W . Extending the elderly- and risk-group programme of vaccination against seasonal influenza in England and Wales: a cost-effectiveness study. BMC Med. 2015; 13:236. PMC: 4604076. DOI: 10.1186/s12916-015-0452-y. View

10.

Cassini A, Hogberg L, Plachouras D, Quattrocchi A, Hoxha A, Simonsen G . Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis. Lancet Infect Dis. 2018; 19(1):56-66. PMC: 6300481. DOI: 10.1016/S1473-3099(18)30605-4. View

11.

Hardelid P, Ghebremichael-Weldeselassie Y, Whitaker H, Rait G, Gilbert R, Petersen I . Effectiveness of live attenuated influenza vaccine in preventing amoxicillin prescribing in preschool children: a self-controlled case series study. J Antimicrob Chemother. 2017; 73(3):779-786. DOI: 10.1093/jac/dkx463. View

12.

Hayward A, Fragaszy E, Bermingham A, Wang L, Copas A, Edmunds W . Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respir Med. 2014; 2(6):445-54. PMC: 7164821. DOI: 10.1016/S2213-2600(14)70034-7. View

13.

Fleming D, Taylor R, Haguinet F, Schuck-Paim C, Logie J, Webb D . Influenza-attributable burden in United Kingdom primary care. Epidemiol Infect. 2015; 144(3):537-47. PMC: 4714299. DOI: 10.1017/S0950268815001119. View

14.

Pebody R, Green H, Andrews N, Boddington N, Zhao H, Yonova I . Uptake and impact of vaccinating school age children against influenza during a season with circulation of drifted influenza A and B strains, England, 2014/15. Euro Surveill. 2015; 20(39). DOI: 10.2807/1560-7917.ES.2015.20.39.30029. View