Recent Progress Regarding Kaempferol for the Treatment of Various Diseases

Overview

Journal Exp Ther Med

Specialty Pathology

Date 2019 Oct 2

PMID 31572524

Citations 136

Authors

Jie Ren

Yifei Lu

Yanhong Qian

Bozhou Chen

Tao Wu

Guang Ji

Affiliations

Soon will be listed here.

Abstract

Kaempferol, also known as kaempferol-3 or kaempferide, is a flavonoid compound that naturally occurs in tea, as well as numerous common vegetables and fruits, including beans, broccoli, cabbage, gooseberries, grapes, kale, strawberries, tomatoes, citrus fruits, brussel sprouts, apples and grapefruit. The present review mainly summarizes the application of kaempferol in treating diseases and the underlying mechanisms that are currently being studied. Due to its anti-inflammatory properties, it may be used to treat numerous acute and chronic inflammation-induced diseases, including intervertebral disc degeneration and colitis, as well as post-menopausal bone loss and acute lung injury. In addition, it has beneficial effects against cancer, liver injury, obesity and diabetes, inhibits vascular endothelial inflammation, protects the cranial nerve and heart function, and may be used for treating fibroproliferative disorders, including hypertrophic scar.

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