Base Metal-Catalyzed Direct Olefinations of Alcohols with Sulfones

Overview

Journal ACS Omega

Publisher American Chemical Society

Specialty Chemistry

Date 2019 Aug 29

PMID 31459819

Citations 2

Authors

Satyadeep Waiba

Animesh Das

Milan K Barman

Biplab Maji

Affiliations

Soon will be listed here.

Abstract

Herein, a base-metal nickel-catalyzed direct olefination of alcohols with sulfones is reported. The reaction operates under low catalyst loading and does not require an external redox reagent. A wide range of -stilbenes and styrenes were synthesized in good yields and selectivities. Biologically active stilbene could also be synthesized in a single step under these conditions. Mechanistic studies involving kinetic isotope effect, deuterium labeling experiments, and catalytic and stoichiometric reactions with possible catalytic intermediates were performed to elucidate a plausible mechanism.

Citing Articles

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