A Risk Score Predicting New Incidence of Hypertension in Japan
Overview
Authors
Affiliations
The prevention of hypertension starts with the awareness of risk. Our aim was to construct a simple and well-validated risk model for nonhypertensive people in Japan consisting of basic clinical variables, using a dataset for two areas derived from the Japan Multi-Institutional Collaborative Cohort Study. We constructed a continuous-value model using data on 5105 subjects participating in both the baseline survey and a second survey conducted after 5 years. The area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow χ statistic for the entire cohort were 0.826 and 7.06, respectively. For validation, the entire cohort was randomly divided 100 times into derivation and validation sets at a ratio of 6:4. The summarized median AUC and the Hosmer-Lemeshow χ statistic were 0.83 and 12.2, respectively. The AUC of a point-based model consisting of integer scores assigned to each variable was 0.826 and showed no difference, compared with the continuous-value model. This simple risk model may help the general population to assess their risks of new-onset hypertension.
Prognostic risk models for incident hypertension: A PRISMA systematic review and meta-analysis.
Schjerven F, Lindseth F, Steinsland I PLoS One. 2024; 19(3):e0294148.
PMID: 38466745 PMC: 10927109. DOI: 10.1371/journal.pone.0294148.
Development of risk models of incident hypertension using machine learning on the HUNT study data.
Schjerven F, Ingestrom E, Steinsland I, Lindseth F Sci Rep. 2024; 14(1):5609.
PMID: 38454041 PMC: 10920790. DOI: 10.1038/s41598-024-56170-7.
Chowdhury M, Leung A, Walker R, Sikdar K, OBeirne M, Quan H Sci Rep. 2023; 13(1):13.
PMID: 36593280 PMC: 9807553. DOI: 10.1038/s41598-022-27264-x.
The relationship between lipid risk score and new-onset hypertension in a prospective cohort study.
Xie H, Zhuang Q, Mu J, Sun J, Wei P, Zhao X Front Endocrinol (Lausanne). 2022; 13:916951.
PMID: 36246874 PMC: 9555054. DOI: 10.3389/fendo.2022.916951.
Chowdhury M, Leung A, Sikdar K, OBeirne M, Quan H, Turin T Sci Rep. 2022; 12(1):12780.
PMID: 35896590 PMC: 9329335. DOI: 10.1038/s41598-022-16904-x.