Characterization Of Secondary Metabolites From The Rhizome Of And Their Antioxidant Properties
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The aerial portions of commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studies of CSR have been reported to date. The purpose of this research was to identify the active components from CSR through bioassay-guided fractionation. The antioxidant properties of secondary metabolites - were evaluated in this investigation. Compounds -, , and showed antioxidant activities based on DPPH free radical scavenging activity with IC values of 22.91-147.21 μM. Besides, compound significantly and dose-dependently reduced HO-induced ROS levels in keratinocyte HaCaT cells without cytotoxicity toward HaCaT. Overall, our studies demonstrated the rhizome of could be used as a new natural antioxidant like the edible aerial portions and phenolic compounds are the active components.
El-Nashar H, Abbas H, Zewail M, Noureldin M, Ali M, Shamaa M Pharmaceuticals (Basel). 2022; 15(10).
PMID: 36297313 PMC: 9610800. DOI: 10.3390/ph15101202.