Pnmt-Derived Cardiomyocytes: Anatomical Localization, Function and Future Perspectives

Overview

Journal Front Physiol

Date 2019 Jul 30

PMID 31354504

Citations 1

Authors

Xuehui Fan

Tianyi Sun

William Crawford

Xiaoqiu Tan

Xianhong Ou

Derek A Terrar

Steven N Ebert

Ming Lei

Affiliations

Soon will be listed here.

Abstract

In this mini-review, we provide an overview of phenylethanolamine-N-methyl transferase (Pnmt)-derived cardiomyocytes (PdCMs), a recently discovered cardiomyocyte subpopulation. We discuss their anatomical localization, physiological characteristics, possible function, and future perspectives. Their unique distribution in the heart, electrical activity, Ca transient properties, and potential role in localized adrenergic signaling are discussed.

Citing Articles

Novel cardiac cell subpopulations: Pnmt-derived cardiomyocytes.

Grassam-Rowe A, Ou X, Lei M Open Biol. 2020; 10(8):200095.

PMID: 32810421 PMC: 7479933. DOI: 10.1098/rsob.200095.

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