Transgenic RXLR Effector Suppresses Immunity and Reduces Vegetative Growth in Potato

causes the severe late blight disease of potato. During its infection process, delivers hundreds of RXLR (Arg-x-Leu-Arg, x behalf of any one amino acid) effectors to manipulate processes in its hosts, creating a suitable environment for invasion and proliferation. Several effectors interact with host proteins to suppress host immunity and inhibit plant growth. However, little is known about how regulates the host transcriptome. Here, we identified an RXLR effector, , which is upregulated and maintains a high expression level throughout the infection. Stable transgenic potato () lines expressing show enhanced leaf colonization by and reduced vegetative growth. We further investigated the transcriptional changes between three transgenic lines and the wild type Désirée by using RNA sequencing (RNA-Seq). Compared with Désirée, 190 differentially expressed genes (DEGs) were identified, including 158 upregulated genes and 32 downregulated genes in transgenic lines. Eight upregulated and nine downregulated DEGs were validated by real-time RT-PCR, which showed a high correlation with the expression level identified by RNA-Seq. These DEGs will help to explore the mechanism of PITG_15718.2-mediated immunity and growth inhibition in the future.