» Articles » PMID: 31161059

()-3-({[3-Meth-oxy-5-(tri-fluoro-meth-yl)phen-yl]imino}meth-yl)benzene-1,2-diol

Overview
Date 2019 Jun 5
PMID 31161059
Citations 2
Authors
Affiliations
Soon will be listed here.
Abstract

The title compound, CHFNO, crystallizes with one mol-ecule in the asymmetric unit. The mean planes of the two phenyl rings of the Schiff base moiety, bearing the OH groups and the imine group, respectively, are inclined to each other by 4.91 (1)°. In the crystal, mol-ecules are linked pairs of bifurcated O-H⋯O hydrogen bonds between the phenol OH groups, forming inversion dimers with an (5) ring motif. The structure exhibits also intra-molecular O-H⋯N and C-H⋯F hydrogen-bonding inter-actions. Hirshfeld surfaces analysis and two-dimensional fingerprint plots were applied to qu-antify the inter-molecular inter-actions. The three F atoms of the tri-fluoro-methyl group are disordered over two sets of sites, with occupancy factors of 0.578 (8) and 0.422 (8). The crystal studied was refined as an inversion twin.

Citing Articles

Synthesis, Characterizations, Hirshfeld Surface Analysis, DFT, and NLO Study of a Schiff Base Derived from Trifluoromethyl Amine.

Tahir M, Ashfaq M, Munawar K, Khan A, Asghar M, Ahamad T ACS Omega. 2024; 9(2):2325-2338.

PMID: 38250356 PMC: 10795116. DOI: 10.1021/acsomega.3c05199.


Crystal structure and Hirshfeld surface analysis of 2-{[()-(3-cyclo-butyl-1-1,2,4-triazol-5-yl)imino]-meth-yl}phenol.

Gumus M, Sen F, Kansiz S, Dege N, Saif E Acta Crystallogr E Crystallogr Commun. 2021; 77(Pt 12):1267-1271.

PMID: 34925895 PMC: 8647728. DOI: 10.1107/S2056989021011658.

References
1.
Tufekci M, Alpaslan Y, Macit M, Erdonmez A . (E)-2-[(4-Chloro-phen-yl)imino-meth-yl]-4-(trifluoro-meth-oxy)phenol. Acta Crystallogr Sect E Struct Rep Online. 2011; 65(Pt 11):o2704. PMC: 2971205. DOI: 10.1107/S1600536809040690. View

2.
Spek A . Structure validation in chemical crystallography. Acta Crystallogr D Biol Crystallogr. 2009; 65(Pt 2):148-55. PMC: 2631630. DOI: 10.1107/S090744490804362X. View

3.
Vanco J, Svajlenova O, Ramanska E, Muselik J, Valentova J . Antiradical activity of different copper(II) Schiff base complexes and their effect on alloxan-induced diabetes. J Trace Elem Med Biol. 2005; 18(2):155-61. DOI: 10.1016/j.jtemb.2004.07.003. View

4.
Karadayi N, Sahin S, Koysal Y, Coskun E, Buyukgungor O . Crystal structure of 2-{[2-meth-oxy-5-(tri-fluoro-meth-yl)phen-yl]iminomethyl}-4-nitro-phenol. Acta Crystallogr E Crystallogr Commun. 2015; 71(Pt 7):o466-7. PMC: 4518952. DOI: 10.1107/S2056989015010129. View

5.
Groom C, Bruno I, Lightfoot M, Ward S . The Cambridge Structural Database. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2016; 72(Pt 2):171-9. PMC: 4822653. DOI: 10.1107/S2052520616003954. View