Circulating MiRNAs As Biomarkers for Endometriosis and Endometriosis-Related Ovarian Cancer-An Overview

Overview

Journal J Clin Med

Specialty General Medicine

Date 2019 May 26

PMID 31126056

Citations 28

Authors

Marius Alexandru Moga

Andreea Balan

Oana Gabriela Dimienescu

Victoria Burtea

Roxana Maria Dragomir

Costin Vlad Anastasiu

Affiliations

Soon will be listed here.

Abstract

Methods: We selected the reviewed papers from Google Academic, PubMed, and CrossRef. A total of eight studies met the inclusion criteria.

Results: MiR-200 family, miR-143, 145, miR-20a, and miR199a were the most commonly dysregulated miRNAs in endometriosis, and miR-200 family was found to be dysregulated in both ERONs and endometriosis.

Conclusions: No single miRNA was considered as a sole biomarker for this pathology. However, since the prognostic value of biomarkers is generally enhanced if more are assessed at the same time, a panel of miRNAs could be a better indicator of the disease.

Citing Articles

Advances in research on malignant transformation of endometriosis-associated ovarian cancer.

Chen F, Zhu M, Li W Front Oncol. 2024; 14:1475231.

PMID: 39445058 PMC: 11496038. DOI: 10.3389/fonc.2024.1475231.

Diagnostic Value and Molecular Function of MicroRNAs in Endometrial Diseases: A Systematic Review.

Kluz N, Kowalczyk E, Wasilewska M, Gil-Kulik P Cancers (Basel). 2024; 16(13).

PMID: 39001478 PMC: 11240806. DOI: 10.3390/cancers16132416.

Immune pathway through endometriosis to ovarian cancer.

Santos Calmon M, Bueno Lemos F, Silva Luz M, Rocha Pinheiro S, de Oliveira Silva L, Lima Correa Santos G World J Clin Oncol. 2024; 15(4):496-522.

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Endometriosis-Related Ovarian Cancer: Where Are We Now? A Narrative Review towards a Pragmatic Approach.

Centini G, Schettini G, Pieri E, Giorgi M, Lazzeri L, Martire F J Clin Med. 2024; 13(7).

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miRNA Expression Profiles in Ovarian Endometriosis and Two Types of Ovarian Cancer-Endometriosis-Associated Ovarian Cancer and High-Grade Ovarian Cancer.

Szubert M, Nowak-Gluck A, Domanska-Senderowska D, Szymanska B, Sowa P, Rycerz A Int J Mol Sci. 2023; 24(24).

PMID: 38139300 PMC: 10743418. DOI: 10.3390/ijms242417470.

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