Role of Biofilms in Children with Chronic Adenoiditis and Middle Ear Disease

Overview

Journal J Clin Med

Specialty General Medicine

Date 2019 May 16

PMID 31086039

Citations 8

Authors

Sara Torretta

Lorenzo Drago

Paola Marchisio

Tullio Ibba

Lorenzo Pignataro

Affiliations

Soon will be listed here.

Abstract

Chronic adenoiditis occurs frequently in children, and it is complicated by the subsequent development of recurrent or chronic middle ear diseases, such as recurrent acute otitis media, persistent otitis media with effusion and chronic otitis media, which may predispose a child to long-term functional sequalae and auditory impairment. Children with chronic adenoidal disease who fail to respond to traditional antibiotic therapy are usually candidates for surgery under general anaesthesia. It has been suggested that the ineffectiveness of antibiotic therapy in children with chronic adenoiditis is partially related to nasopharyngeal bacterial biofilms, which play a role in the development of chronic nasopharyngeal inflammation due to chronic adenoiditis, which is possibly associated with chronic or recurrent middle ear disease. This paper reviews the current evidence concerning the involvement of bacterial biofilms in the development of chronic adenoiditis and related middle ear infections in children.

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