Research Progress of [Ga]Citrate PET's Utility in Infection and Inflammation Imaging: a Review

Overview

Journal Mol Imaging Biol

Publisher Springer

Specialties Molecular Biology
Radiology

Date 2019 May 12

PMID 31076971

Citations 7

Authors

Tingting Xu

Yue Chen

Affiliations

Soon will be listed here.

Abstract

Imaging diagnosis of infection and inflammation has been challenging for many years. Infection imaging agents commonly used in nuclear medicine, such as [Ga]citrate, 2-deoxy-2-[F]fluoro-D-glucose ([F]FDG), and radionuclide-labeled leukocytes, have their own shortcomings. Identification of a tracer with considerable economic benefit, high specificity, and low radiation dose has become clinically urgent. In the twenty-first century, with the increasing availability of positron emission tomography (PET) devices and the commercialization of Ge-68/Ga-68 generators, the study of [Ga]citrate applications for infection and inflammation has increased and shown good potential. In this report, the research progress that supports [Ga]citrate PET's applications various infectious diseases and inflammation is reviewed.

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