Phage-Based Artificial Niche: The Recent Progress and Future Opportunities in Stem Cell Therapy

Overview

Journal Stem Cells Int

Publisher Wiley

Specialty Cell Biology

Date 2019 May 11

PMID 31073312

Citations 4

Authors

Kshitiz Raj Shrestha

So Young Yoo

Affiliations

Soon will be listed here.

Abstract

Self-renewal and differentiation of stem cells can be the best option for treating intractable diseases in regenerative medicine, and they occur when these cells reside in a special microenvironment, called the "stem cell niche." Thus, the niche is crucial for the effective performance of the stem cells in both and since the niche provides its functional cues by interacting with stem cells chemically, physically, or topologically. This review provides a perspective on the different types of artificial niches including engineered phage and how they could be used to recapitulate or manipulate stem cell niches. Phage-based artificial niche engineering as a promising therapeutic strategy for repair and regeneration of tissues is also discussed.

Citing Articles

Designing molecules: directing stem cell differentiation.

Thanaskody K, Natashah F, Nordin F, Wan Kamarul Zaman W, Tye G Front Bioeng Biotechnol. 2024; 12:1396405.

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Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy.

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