Gelatin-stabilized Composites of Silver Nanoparticles and Curcumin: Characterization, Antibacterial and Antioxidant Study

Overview

Journal Sci Technol Adv Mater

Specialty Biomedical Engineering

Date 2019 May 10

PMID 31068981

Citations 12

Authors

Ly Loan Khanh

Nguyen Thanh Truc

Nguyen Tan Dat

Nguyen Thi Phuong Nghi

Vo Van Toi

Nguyen Thi Thu Hoai

Tran Ngoc Quyen

Tran Thi Thanh Loan

Nguyen Thi Hiep

Affiliations

Soon will be listed here.

Abstract

This is a preliminary study of a material comprising gelatin (Gel), silver nanoparticles (AgNPs) and curcumin (Cur) aimed for wound-healing treatment. Gelatin was used to stabilize AgNPs and encapsulate curcumin to form a therapeutic composite (GelCurAg) for their strong bactericidal and antioxidant properties. GelCurAg formulations with different gelatin concentrations were characterized to attain information about their physiochemical properties and the loading efficiency of therapeutic agents. assessment of GelCurAg focused on antibacterial, antioxidant and cytotoxic aspects. The results suggested that GelCurAg (synthesized from 1% gelatin solution) could be utilized as potential therapeutic agents in treating infectious wound owing to its bactericidal and antioxidant effects and low toxicity for clinical uses.

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