Ready-to-Use Supplemental Food for Nutritional Supplementation in Cystic Fibrosis

Overview

Journal Curr Dev Nutr

Specialty Nutritional Sciences

Date 2019 Apr 24

PMID 31011716

Citations 1

Authors

Ryan T Pitman

Melody Mui

Peter H Michelson

Mark J Manary

Affiliations

Soon will be listed here.

Abstract

Undernutrition is common in cystic fibrosis (CF) and is correlated with long-term outcomes, yet current nutritional interventions have not demonstrated consistent improvements in energy intake, and subsequently, growth. Development of novel nutritional interventions to increase energy intake is essential to improve clinical outcomes of individuals with CF. Ready-to-use supplemental food (RUSF) is a modifiable, inexpensive, palatable, safe, and nutrient-dense food for treatment or prevention of acute malnutrition in developing countries. Utilizing a linear-programming tool we identified 6 RUSF formulations with sufficient nutrient density (495 kcal/100 g), protein, and fat for children with CF. Palatability was established by a taste-trial and affirmed by a 2-wk tolerability assessment that demonstrated consistent consumption and tolerance of the RUSF. Although preliminary, this study demonstrates the potential for developing RUSF as a nutritional supplement for increasing energy intake in children with CF.

Citing Articles

Adherence to Dietary Recommendations, Nutrient Intake Adequacy and Diet Quality among Pediatric Cystic Fibrosis Patients: Results from the GreeCF Study.

Poulimeneas D, Grammatikopoulou M, Devetzi P, Petrocheilou A, Kaditis A, Papamitsou T Nutrients. 2020; 12(10).

PMID: 33066268 PMC: 7602117. DOI: 10.3390/nu12103126.

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