in the Respiratory Tract Potentially Triggers Galactomannan Positivity in Nonhematological Patients

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2019 Apr 3

PMID 30936100

Citations 12

Authors

M Aigner

M Wanner

P Kreidl

C Lass-Florl

M Lackner

Affiliations

Soon will be listed here.

Abstract

BAL fluid samples from critically ill patients shared a rate of 29% false-positive galactomannan results. We aimed to determine whether species abundance in BAL fluid causes galactomannan (GM) positivity. A total of 89 culture-positive BAL fluid samples from patients without suspicion of invasive aspergillosis (IA) were analyzed. GM results were correlated with species abundance, species quantity, and patient data. species quantities of ≥10/ml and abundance were significantly associated with positive GM results. The added diagnostic value of GM in BAL fluid for diagnosing IA in critically ill patients is limited.

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