There Is No "Stem Cell Mess"

Overview

Journal Tissue Eng Part B Rev

Specialties Anatomy & Histology
Biotechnology

Date 2019 Mar 20

PMID 30887883

Citations 16

Authors

Arnold I Caplan

Affiliations

Soon will be listed here.

Abstract

The impact should encourage continued research and clinical trials using mesenchymal stem cells.

Citing Articles

The role of mesenchymal stem cells in cancer and prospects for their use in cancer therapeutics.

Tang J, Chen Y, Wang C, Xia Y, Yu T, Tang M MedComm (2020). 2024; 5(8):e663.

PMID: 39070181 PMC: 11283587. DOI: 10.1002/mco2.663.

Clinical Evaluation of Safety and Efficacy of a Central Current Good Manufacturing Practices Laboratory Produced Autologous Adipose-Derived Stromal Vascular Fraction Cell Therapy Product for the Treatment of Knee Osteoarthritis.

Rogers C, Harman R, Sheinkop M, Hanson P, Ambach M, David T Stem Cells Dev. 2024; 33(7-8):168-176.

PMID: 38386505 PMC: 11036882. DOI: 10.1089/scd.2024.0008.

Effects of Atrazine exposure on human bone marrow-derived mesenchymal stromal cells assessed by combinatorial assay matrix.

Uwazie C, Pirlot B, Faircloth T, Patel M, Parr R, Zastre H Front Immunol. 2023; 14:1214098.

PMID: 37588595 PMC: 10426140. DOI: 10.3389/fimmu.2023.1214098.

The potential therapeutic role of extracellular vesicles in critical-size bone defects: Spring of cell-free regenerative medicine is coming.

Liu F, Sun T, An Y, Ming L, Li Y, Zhou Z Front Bioeng Biotechnol. 2023; 11:1050916.

PMID: 36733961 PMC: 9887316. DOI: 10.3389/fbioe.2023.1050916.

Cellular expansion of MSCs: Shifting the regenerative potential.

Miclau K, Hambright W, Huard J, Stoddart M, Bahney C Aging Cell. 2022; 22(1):e13759.

PMID: 36536521 PMC: 9835588. DOI: 10.1111/acel.13759.

References

Black L, Gaynor J, Gahring D, Adams C, Aron D, Harman S . Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial. Vet Ther. 2008; 8(4):272-84. View

Yoo J, Barthel T, Nishimura K, Solchaga L, Caplan A, Goldberg V . The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg Am. 1999; 80(12):1745-57. DOI: 10.2106/00004623-199812000-00004. View

Caplan A . What's in a name?. Tissue Eng Part A. 2010; 16(8):2415-7. DOI: 10.1089/ten.TEA.2010.0216. View

Tropel P, Platet N, Platel J, Noel D, Albrieux M, Benabid A . Functional neuronal differentiation of bone marrow-derived mesenchymal stem cells. Stem Cells. 2006; 24(12):2868-76. DOI: 10.1634/stemcells.2005-0636. View

Caplan A . Mesenchymal stem cells. J Orthop Res. 1991; 9(5):641-50. DOI: 10.1002/jor.1100090504. View

Jaiswal N, Haynesworth S, Caplan A, Bruder S . Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem. 1997; 64(2):295-312. View

Sorrell J, Somoza R, Caplan A . Human mesenchymal stem cells induced to differentiate as chondrocytes follow a biphasic pattern of extracellular matrix production. J Orthop Res. 2017; 36(6):1757-1766. PMC: 5976510. DOI: 10.1002/jor.23820. View

Galipeau J, Sensebe L . Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities. Cell Stem Cell. 2018; 22(6):824-833. PMC: 6434696. DOI: 10.1016/j.stem.2018.05.004. View

Kenyon J, Sergeeva O, Somoza R, Li M, Caplan A, Khalil A . Analysis of -5p and -3p Strands of miR-145 and miR-140 During Mesenchymal Stem Cell Chondrogenic Differentiation. Tissue Eng Part A. 2018; 25(1-2):80-90. PMC: 6352508. DOI: 10.1089/ten.TEA.2017.0440. View

10.

Guimaraes-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton N . Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017; 20(3):345-359.e5. PMC: 5337131. DOI: 10.1016/j.stem.2016.12.006. View

11.

Wakitani S, Saito T, Caplan A . Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve. 1995; 18(12):1417-26. DOI: 10.1002/mus.880181212. View

12.

Barry F, Murphy J . Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol. 2004; 36(4):568-84. DOI: 10.1016/j.biocel.2003.11.001. View

13.

Vickers E, Karsten E, Flood J, Lilischkis R . A preliminary report on stem cell therapy for neuropathic pain in humans. J Pain Res. 2014; 7:255-63. PMC: 4020887. DOI: 10.2147/JPR.S63361. View

14.

Squillaro T, Peluso G, Galderisi U . Clinical Trials With Mesenchymal Stem Cells: An Update. Cell Transplant. 2015; 25(5):829-48. DOI: 10.3727/096368915X689622. View

15.

Bagno L, Hatzistergos K, Balkan W, Hare J . Mesenchymal Stem Cell-Based Therapy for Cardiovascular Disease: Progress and Challenges. Mol Ther. 2018; 26(7):1610-1623. PMC: 6037203. DOI: 10.1016/j.ymthe.2018.05.009. View

16.

Dennis J, Merriam A, Awadallah A, Yoo J, Johnstone B, Caplan A . A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse. J Bone Miner Res. 1999; 14(5):700-9. DOI: 10.1359/jbmr.1999.14.5.700. View

17.

Sipp D, Robey P, Turner L . Clear up this stem-cell mess. Nature. 2018; 561(7724):455-457. DOI: 10.1038/d41586-018-06756-9. View