Low Mortality and Short-term Morbidity in Very Preterm Infants in Austria 2011-2016

Overview

Journal Acta Paediatr

Specialty Pediatrics

Date 2019 Mar 1

PMID 30817025

Citations 10

Authors

U Kiechl-Kohlendorfer

B Simma

B Urlesberger

U Maurer-Fellbaum

M Wald

M Weissensteiner

D Ehringer-Schetitska

A Berger

Affiliations

Soon will be listed here.

Abstract

Aim: The current study determined survival, short-term neonatal morbidity and predictors for death or adverse outcome of very preterm infants in Austria.

Methods: This population-based cohort study included 5197 very preterm infants (53.3% boys) born between 2011 and 2016 recruited from the Austrian Preterm Outcome Registry. Main outcome measures were gestational age-related mortality and major short-term morbidities.

Results: Overall, survival rate of all live-born infants included was 91.6% and ranged from 47.1% and 73.4% among those born at 23 and 24 weeks of gestation to 84.9% and 88.2% among infants born at 25 and 26 weeks to more than 90.0% among those with a gestational age of 27 weeks or more. The overall prevalence of chronic lung disease, necrotising enterocolitis requiring surgery, intraventricular haemorrhage Grades 3-4, and retinopathy of prematurity Grades 3-5 was 10.0%, 2.1%, 5.5%, and 3.6%, respectively. Low gestational age, low birth weight, missing or incomplete course of antenatal steroids, male sex, and multiple births were significant risk predictors for death or adverse short-term outcome.

Conclusion: In this national cohort study, overall survival rates were high and short-term morbidity rate was low.

Citing Articles

Survival outcomes among periviable infants: a systematic review and meta-analysis comparing different income countries and time periods.

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Withdrawal and withholding of life sustaining treatment (WWLST): an under recognised factor in the morbidity or mortality of periviable infants?-a narrative review.

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Survival and morbidity in very preterm infants in Shenzhen: a multi-center study.

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Outcome in very preterm infants: a population-based study from a regional center in Austria.

Konzett K, Riedl D, Blassnig-Ezeh A, Gang S, Simma B Front Pediatr. 2024; 12:1336469.

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Response to Therapeutic Interventions in the NICU: Role of Sex as a Biological Variable.

Albert R, Lee A, Lingappan K Neoreviews. 2023; 24(12):e797-e805.

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