Highlight Report: Toxicogenomics Atlas of Rat Hepatotoxicants
Overview
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
References
1.
Stemmer K, Ellinger-Ziegelbauer H, Ahr H, Dietrich D
. Carcinogen-specific gene expression profiles in short-term treated Eker and wild-type rats indicative of pathways involved in renal tumorigenesis. Cancer Res. 2007; 67(9):4052-68.
DOI: 10.1158/0008-5472.CAN-06-3587.
View
2.
Ellinger-Ziegelbauer H, Adler M, Amberg A, Brandenburg A, Callanan J, Connor S
. The enhanced value of combining conventional and "omics" analyses in early assessment of drug-induced hepatobiliary injury. Toxicol Appl Pharmacol. 2010; 252(2):97-111.
DOI: 10.1016/j.taap.2010.09.022.
View
3.
Godoy P, Hewitt N, Albrecht U, Andersen M, Ansari N, Bhattacharya S
. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol. 2013; 87(8):1315-530.
PMC: 3753504.
DOI: 10.1007/s00204-013-1078-5.
View
4.
Waldmann T, Rempel E, Balmer N, Konig A, Kolde R, Gaspar J
. Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells. Chem Res Toxicol. 2014; 27(3):408-20.
PMC: 3958134.
DOI: 10.1021/tx400402j.
View
5.
Balmer N, Klima S, Rempel E, Ivanova V, Kolde R, Weng M
. From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch Toxicol. 2014; 88(7):1451-68.
PMC: 4067541.
DOI: 10.1007/s00204-014-1279-6.
View