The Journey of Hyaluronan Research in the

Overview

Journal J Biol Chem

Specialty Biochemistry

Date 2019 Feb 3

PMID 30710015

Citations 10

Authors

Vincent C Hascall

Affiliations

Soon will be listed here.

Abstract

Hyaluronan has a very simple structure. It is a linear glycosaminoglycan composed of disaccharide units of GlcNAc and d-glucuronic acid with alternating β-1,4 and β-1,3 glycosidic bonds that can be repeated 20,000 or more times, a molecular mass >8 million Da, and a length >20 μm. However, it has a very complex biology. It is a major, ubiquitous component of extracellular matrices involved in everything from fertilization, development, inflammations, to cancer. This JBC Review highlights some of these processes that were initiated through publications in the .

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