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Recent Updates on Cancer Immunotherapy

Overview
Journal Precis Clin Med
Specialty General Medicine
Date 2019 Jan 29
PMID 30687562
Citations 56
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Abstract

Traditional cancer therapies include surgery, radiation, and chemotherapy, all of which are typically non-specific approaches. Cancer immunotherapy is a type of cancer treatment that helps the immune system fight cancer. Cancer immunotherapy represents a standing example of precision medicine: immune checkpoint inhibitors precisely target the checkpoints; tumor infiltrating lymphocytes, TCR T cells, and CAR T cells precisely kill cancer cells through tumor antigen recognition; and cancer vaccines are made from patient-derived dendritic cells, tumor cell DNA, or RNA, or oncolytic viruses, thus offering a type of personalized medicine. This review will highlight up-to-date advancement in most, if not all, of the immunotherapy strategies.

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References
1.
Tanyi J, Bobisse S, Ophir E, Tuyaerts S, Roberti A, Genolet R . Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer. Sci Transl Med. 2018; 10(436). DOI: 10.1126/scitranslmed.aao5931. View

2.
Aspeslagh S, Postel-Vinay S, Rusakiewicz S, Soria J, Zitvogel L, Marabelle A . Rationale for anti-OX40 cancer immunotherapy. Eur J Cancer. 2015; 52:50-66. DOI: 10.1016/j.ejca.2015.08.021. View

3.
Zhang D, Armstrong A, Tam S, McCarthy S, Luo J, Gilliland G . Functional optimization of agonistic antibodies to OX40 receptor with novel Fc mutations to promote antibody multimerization. MAbs. 2017; 9(7):1129-1142. PMC: 5627589. DOI: 10.1080/19420862.2017.1358838. View

4.
Best S, de Souza D, Kersbergen A, Policheni A, Dayalan S, Tull D . Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment. Cell Metab. 2018; 27(4):935-943.e4. DOI: 10.1016/j.cmet.2018.02.006. View

5.
Sharma P, Hu-Lieskovan S, Wargo J, Ribas A . Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy. Cell. 2017; 168(4):707-723. PMC: 5391692. DOI: 10.1016/j.cell.2017.01.017. View