Artificial Intelligence and Integrated Genotype⁻Phenotype Identification

Overview

Journal Genes (Basel)

Publisher MDPI

Date 2019 Jan 2

PMID 30597900

Citations 10

Authors

Lewis J Frey

Affiliations

Soon will be listed here.

Abstract

The integration of phenotypes and genotypes is at an unprecedented level and offers new opportunities to establish deep phenotypes. There are a number of challenges to overcome, specifically, accelerated growth of data, data silos, incompleteness, inaccuracies, and heterogeneity within and across data sources. This perspective report discusses artificial intelligence (AI) approaches that hold promise in addressing these challenges by automating computable phenotypes and integrating them with genotypes. Collaborations between biomedical and AI researchers will be highlighted in order to describe initial successes with an eye toward the future.

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