Effects of the Antiprotease Trasylol on Peripheral Blood Leucocytes

Overview

Journal Experientia

Specialty Science

Date 1978 Apr 15

PMID 305854

Citations 8

Authors

A W Thomson

D J Tweedie

C H Horne

Affiliations

Soon will be listed here.

Abstract

Binding of the antiprotease Trasylol to human peripheral blood lymphocytes and polymorphonuclear leucocytes (PMNs) was demonstrated at the ultrastructural level using an indirect immunoperoxidase technique. This also revealed endocytosis of membrane bound Trasylol by PMNs. Trasylol inhibited PHA- and ConA-induced lymphocyte stimulation, and was cytotoxic to unstimulated cells.

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